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Synthesis and activity of 2-(sulfonamido)methyl-carbapenems: discovery of a novel, anti-MRSA 1,8-naphthosultam pharmacophore.
Wilkening RR, Ratcliffe RW, Wildonger KJ, Cama LD, Dykstra KD, DiNinno FP, Blizzard TA, Hammond ML, Heck JV, Dorso KL, St Rose E, Kohler J, Hammond GG. Wilkening RR, et al. Among authors: hammond ml, hammond gg. Bioorg Med Chem Lett. 1999 Mar 8;9(5):673-8. doi: 10.1016/s0960-894x(99)00070-0. Bioorg Med Chem Lett. 1999. PMID: 10201827
Synthesis and properties of 2-(naphthosultamyl)methyl-carbapenems with potent anti-MRSA activity: discovery of L-786,392.
Ratcliffe RW, Wilkening RR, Wildonger KJ, Waddell ST, Santorelli GM, Parker DL Jr, Morgan JD, Blizzard TA, Hammond ML, Heck JV, Huber J, Kohler J, Dorso KL, St Rose E, Sundelof JG, May WJ, Hammond GG. Ratcliffe RW, et al. Among authors: hammond ml, hammond gg. Bioorg Med Chem Lett. 1999 Mar 8;9(5):679-84. doi: 10.1016/s0960-894x(99)00071-2. Bioorg Med Chem Lett. 1999. PMID: 10201828
Estrogen receptor ligands. Part 3: The SAR of dihydrobenzoxathiin SERMs.
Chen HY, Kim S, Wu JY, Birzin ET, Chan W, Yang YT, Dahllund J, DiNinno F, Rohrer SP, Schaeffer JM, Hammond ML. Chen HY, et al. Among authors: hammond ml. Bioorg Med Chem Lett. 2004 May 17;14(10):2551-4. doi: 10.1016/j.bmcl.2004.02.084. Bioorg Med Chem Lett. 2004. PMID: 15109649
Estrogen receptor ligands. Part 4: The SAR of the syn-dihydrobenzoxathiin SERAMs.
Kim S, Wu J, Chen HY, Birzin ET, Chan W, Yang YT, Colwell L, Li S, Dahllund J, DiNinno F, Rohrer SP, Schaeffer JM, Hammond ML. Kim S, et al. Among authors: hammond ml. Bioorg Med Chem Lett. 2004 Jun 7;14(11):2741-5. doi: 10.1016/j.bmcl.2004.03.074. Bioorg Med Chem Lett. 2004. PMID: 15125925
Estrogen receptor ligands. Part 7: Dihydrobenzoxathiin SERAMs with bicyclic amine side chains.
Blizzard TA, DiNinno F, Morgan JD 2nd, Chen HY, Wu JY, Gude C, Kim S, Chan W, Birzin ET, Tien Yang Y, Pai LY, Zhang Z, Hayes EC, DaSilva CA, Tang W, Rohrer SP, Schaeffer JM, Hammond ML. Blizzard TA, et al. Among authors: hammond ml. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3861-4. doi: 10.1016/j.bmcl.2004.05.074. Bioorg Med Chem Lett. 2004. PMID: 15225685
Estrogen receptor ligands. Part 10: Chromanes: old scaffolds for new SERAMs.
Tan Q, Blizzard TA, Morgan JD 2nd, Birzin ET, Chan W, Yang YT, Pai LY, Hayes EC, DaSilva CA, Warrier S, Yudkovitz J, Wilkinson HA, Sharma N, Fitzgerald PM, Li S, Colwell L, Fisher JE, Adamski S, Reszka AA, Kimmel D, DiNinno F, Rohrer SP, Freedman LP, Schaeffer JM, Hammond ML. Tan Q, et al. Among authors: hammond ml. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1675-81. doi: 10.1016/j.bmcl.2005.01.046. Bioorg Med Chem Lett. 2005. PMID: 15745820
99 results