Shepherd PR - Search Results

1

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

Navé BT, Ouwens M, Withers DJ, Alessi DR, Shepherd PR. Navé BT, et al. Among authors: shepherd pr. Biochem J. 1999 Dec 1;344 Pt 2(Pt 2):427-31. Biochem J. 1999. PMID: 10567225 Free PMC article.

2

Involvement of phosphoinositide 3-kinase in insulin stimulation of MAP-kinase and phosphorylation of protein kinase-B in human skeletal muscle: implications for glucose metabolism.

Shepherd PR, Nave BT, Rincon J, Haigh RJ, Foulstone E, Proud C, Zierath JR, Siddle K, Wallberg-Henriksson H. Shepherd PR, et al. Diabetologia. 1997 Oct;40(10):1172-7. doi: 10.1007/s001250050803. Diabetologia. 1997. PMID: 9349598

3

Is stimulation of class-1 phosphatidylinositol 3-kinase activity by insulin sufficient to activate pathways involved in glucose metabolism.

Shepherd PR, Siddle K, Navé BT. Shepherd PR, et al. Biochem Soc Trans. 1997 Aug;25(3):978-81. doi: 10.1042/bst0250978. Biochem Soc Trans. 1997. PMID: 9388585 Review.

4

Expression, enzyme activity, and subcellular localization of mammalian target of rapamycin in insulin-responsive cells.

Withers DJ, Ouwens DM, Nave BT, van der Zon GC, Alarcon CM, Cardenas ME, Heitman J, Maassen JA, Shepherd PR. Withers DJ, et al. Among authors: shepherd pr. Biochem Biophys Res Commun. 1997 Dec 29;241(3):704-9. doi: 10.1006/bbrc.1997.7878. Biochem Biophys Res Commun. 1997. PMID: 9434772

5

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling.

Shepherd PR, Withers DJ, Siddle K. Shepherd PR, et al. Biochem J. 1998 Aug 1;333 ( Pt 3)(Pt 3):471-90. doi: 10.1042/bj3330471. Biochem J. 1998. PMID: 9677303 Free PMC article. Review.

6

Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase.

Shepherd PR, Navé BT, Siddle K. Shepherd PR, et al. Biochem J. 1995 Jan 1;305 ( Pt 1)(Pt 1):25-8. doi: 10.1042/bj3050025. Biochem J. 1995. PMID: 7826337 Free PMC article.

7

Compartment-specific regulation of phosphoinositide 3-kinase by platelet-derived growth factor and insulin in 3T3-L1 adipocytes.

Navé BT, Haigh RJ, Hayward AC, Siddle K, Shepherd PR. Navé BT, et al. Among authors: shepherd pr. Biochem J. 1996 Aug 15;318 ( Pt 1)(Pt 1):55-60. doi: 10.1042/bj3180055. Biochem J. 1996. PMID: 8761452 Free PMC article.

8

Phorbol esters stimulate phosphatidylinositol 3,4,5-trisphosphate production in 3T3-L1 adipocytes: implications for stimulation of glucose transport.

Navé BT, Siddle K, Shepherd PR. Navé BT, et al. Among authors: shepherd pr. Biochem J. 1996 Aug 15;318 ( Pt 1)(Pt 1):203-5. doi: 10.1042/bj3180203. Biochem J. 1996. PMID: 8761472 Free PMC article.

9

The role of phosphoinositide 3-kinase in insulin signalling.

Shepherd PR, Navé BT, O'Rahilly S. Shepherd PR, et al. J Mol Endocrinol. 1996 Dec;17(3):175-84. doi: 10.1677/jme.0.0170175. J Mol Endocrinol. 1996. PMID: 8981224 Review. No abstract available.

10

Differential regulation of phosphoinositide 3-kinase adapter subunit variants by insulin in human skeletal muscle.

Shepherd PR, Navé BT, Rincon J, Nolte LA, Bevan AP, Siddle K, Zierath JR, Wallberg-Henriksson H. Shepherd PR, et al. J Biol Chem. 1997 Jul 25;272(30):19000-7. doi: 10.1074/jbc.272.30.19000. J Biol Chem. 1997. PMID: 9228082 Free article.

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