Howley PM - Search Results

1

Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade.

Huang L, Kinnucan E, Wang G, Beaudenon S, Howley PM, Huibregtse JM, Pavletich NP. Huang L, et al. Among authors: howley pm. Science. 1999 Nov 12;286(5443):1321-6. doi: 10.1126/science.286.5443.1321. Science. 1999. PMID: 10558980

2

Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53.

Scheffner M, Huibregtse JM, Howley PM. Scheffner M, et al. Among authors: howley pm. Proc Natl Acad Sci U S A. 1994 Sep 13;91(19):8797-801. doi: 10.1073/pnas.91.19.8797. Proc Natl Acad Sci U S A. 1994. PMID: 8090726 Free PMC article.

3

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53.

Scheffner M, Huibregtse JM, Vierstra RD, Howley PM. Scheffner M, et al. Among authors: howley pm. Cell. 1993 Nov 5;75(3):495-505. doi: 10.1016/0092-8674(93)90384-3. Cell. 1993. PMID: 8221889

4

Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins.

Huibregtse JM, Scheffner M, Howley PM. Huibregtse JM, et al. Among authors: howley pm. Mol Cell Biol. 1993 Aug;13(8):4918-27. doi: 10.1128/mcb.13.8.4918-4927.1993. Mol Cell Biol. 1993. PMID: 8393140 Free PMC article.

5

The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells.

Talis AL, Huibregtse JM, Howley PM. Talis AL, et al. Among authors: howley pm. J Biol Chem. 1998 Mar 13;273(11):6439-45. doi: 10.1074/jbc.273.11.6439. J Biol Chem. 1998. PMID: 9497376 Free article.

6

Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase.

Kao WH, Beaudenon SL, Talis AL, Huibregtse JM, Howley PM. Kao WH, et al. Among authors: howley pm. J Virol. 2000 Jul;74(14):6408-17. doi: 10.1128/jvi.74.14.6408-6417.2000. J Virol. 2000. PMID: 10864652 Free PMC article.

7

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase.

Huibregtse JM, Scheffner M, Beaudenon S, Howley PM. Huibregtse JM, et al. Among authors: howley pm. Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2563-7. doi: 10.1073/pnas.92.7.2563. Proc Natl Acad Sci U S A. 1995. PMID: 7708685 Free PMC article.

8

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

Huibregtse JM, Scheffner M, Howley PM. Huibregtse JM, et al. Among authors: howley pm. Mol Cell Biol. 1993 Feb;13(2):775-84. doi: 10.1128/mcb.13.2.775-784.1993. Mol Cell Biol. 1993. PMID: 8380895 Free PMC article.

9

The human E6-AP gene (UBE3A) encodes three potential protein isoforms generated by differential splicing.

Yamamoto Y, Huibregtse JM, Howley PM. Yamamoto Y, et al. Among authors: howley pm. Genomics. 1997 Apr 15;41(2):263-6. doi: 10.1006/geno.1997.4617. Genomics. 1997. PMID: 9143503

10

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase.

Huibregtse JM, Scheffner M, Beaudenon S, Howley PM. Huibregtse JM, et al. Among authors: howley pm. Proc Natl Acad Sci U S A. 1995 May 23;92(11):5249. doi: 10.1073/pnas.92.11.5249-b. Proc Natl Acad Sci U S A. 1995. PMID: 7761480 Free PMC article. No abstract available.

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