Maga G - Search Results

1

Pyrrolobenzoxazepinone derivatives as non-nucleoside HIV-1 RT inhibitors: further structure-activity relationship studies and identification of more potent broad-spectrum HIV-1 RT inhibitors with antiviral activity.

Campiani G, Morelli E, Fabbrini M, Nacci V, Greco G, Novellino E, Ramunno A, Maga G, Spadari S, Caliendo G, Bergamini A, Faggioli E, Uccella I, Bolacchi F, Marini S, Coletta M, Nacca A, Caccia S. Campiani G, et al. Among authors: maga g. J Med Chem. 1999 Oct 21;42(21):4462-70. doi: 10.1021/jm990150o. J Med Chem. 1999. PMID: 10543890

2

Quantitative structure-activity relationships of N2-phenylguanines as inhibitors of herpes simplex virus thymidine kinases.

Gambino J, Focher F, Hildebrand C, Maga G, Noonan T, Spadari S, Wright G. Gambino J, et al. Among authors: maga g. J Med Chem. 1992 Aug 7;35(16):2979-83. doi: 10.1021/jm00094a007. J Med Chem. 1992. PMID: 1323680

3

L-thymidine is phosphorylated by herpes simplex virus type 1 thymidine kinase and inhibits viral growth.

Spadari S, Maga G, Focher F, Ciarrocchi G, Manservigi R, Arcamone F, Capobianco M, Carcuro A, Colonna F, Iotti S, et al. Spadari S, et al. Among authors: maga g. J Med Chem. 1992 Oct 30;35(22):4214-20. doi: 10.1021/jm00100a029. J Med Chem. 1992. PMID: 1331461

4

Effect of divalent and monovalent cations on calf thymus PCNA-independent DNA polymerase delta and its 3'----5' exonuclease.

Focher F, Verri A, Maga G, Spadari S, Hübscher U. Focher F, et al. Among authors: maga g. FEBS Lett. 1990 Jan 1;259(2):349-52. doi: 10.1016/0014-5793(90)80045-k. FEBS Lett. 1990. PMID: 1967165 Free article.

5

Stereospecificity of human DNA polymerases alpha, beta, gamma, delta and epsilon, HIV-reverse transcriptase, HSV-1 DNA polymerase, calf thymus terminal transferase and Escherichia coli DNA polymerase I in recognizing D- and L-thymidine 5'-triphosphate as substrate.

Focher F, Maga G, Bendiscioli A, Capobianco M, Colonna F, Garbesi A, Spadari S. Focher F, et al. Among authors: maga g. Nucleic Acids Res. 1995 Aug 11;23(15):2840-7. doi: 10.1093/nar/23.15.2840. Nucleic Acids Res. 1995. PMID: 7544886 Free PMC article.

6

Aphidicolin inhibits in vitro the activity of pseudorabies virus (PRV) DNA polymerase and in vivo the viral proliferation.

Verri A, Maga G, Spadari S, Ponti W, Strosselli S, Bonizzi L, Rocchi M, Poli G, Focher F. Verri A, et al. Among authors: maga g. In Vivo. 1994 Nov-Dec;8(6):1041-6. In Vivo. 1994. PMID: 7772734

7

Synthesis, properties, and pharmacokinetic studies of N2-phenylguanine derivatives as inhibitors of herpes simplex virus thymidine kinases.

Xu H, Maga G, Focher F, Smith ER, Spadari S, Gambino J, Wright GE. Xu H, et al. Among authors: maga g. J Med Chem. 1995 Jan 6;38(1):49-57. doi: 10.1021/jm00001a010. J Med Chem. 1995. PMID: 7837239

8

Identification, partial purification and inhibition by guanine analogues of a novel enzymic activity which phosphorylates guanosine to GMP in the protozoan parasite Eimeria tenella.

Maga G, Spadari S, Wright GE, Focher F. Maga G, et al. Biochem J. 1994 Mar 1;298 ( Pt 2)(Pt 2):289-94. doi: 10.1042/bj2980289. Biochem J. 1994. PMID: 8135733 Free PMC article.

9

Lack of stereospecificity of some cellular and viral enzymes involved in the synthesis of deoxyribonucleotides and DNA: molecular basis for the antiviral activity of unnatural L-beta-nucleosides.

Spadari S, Maga G, Verri A, Bendiscioli A, Tondelli L, Capobianco M, Colonna F, Garbesi A, Focher F. Spadari S, et al. Among authors: maga g. Biochimie. 1995;77(11):861-67. doi: 10.1016/0300-9084(95)90004-7. Biochimie. 1995. PMID: 8824765

10

Resistance to nevirapine of HIV-1 reverse transcriptase mutants: loss of stabilizing interactions and thermodynamic or steric barriers are induced by different single amino acid substitutions.

Maga G, Amacker M, Ruel N, Hübscher U, Spadari S. Maga G, et al. J Mol Biol. 1997 Dec 19;274(5):738-47. doi: 10.1006/jmbi.1997.1427. J Mol Biol. 1997. PMID: 9405155

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