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Six-month assessment of a phase I trial of angiogenic gene therapy for the treatment of coronary artery disease using direct intramyocardial administration of an adenovirus vector expressing the VEGF121 cDNA.
Rosengart TK, Lee LY, Patel SR, Kligfield PD, Okin PM, Hackett NR, Isom OW, Crystal RG. Rosengart TK, et al. Among authors: crystal rg. Ann Surg. 1999 Oct;230(4):466-70; discussion 470-2. doi: 10.1097/00000658-199910000-00002. Ann Surg. 1999. PMID: 10522716 Free PMC article. Clinical Trial.
The gene as the drug.
Crystal RG. Crystal RG. Nat Med. 1995 Jan;1(1):15-7. doi: 10.1038/nm0195-15. Nat Med. 1995. PMID: 7584940 No abstract available.
Progress in human gene therapy.
Feuerbach FJ, Crystal RG. Feuerbach FJ, et al. Among authors: crystal rg. Kidney Int. 1996 Jun;49(6):1791-4. doi: 10.1038/ki.1996.269. Kidney Int. 1996. PMID: 8743499 Free article. Review.
Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart.
Mack CA, Patel SR, Schwarz EA, Zanzonico P, Hahn RT, Ilercil A, Devereux RB, Goldsmith SJ, Christian TF, Sanborn TA, Kovesdi I, Hackett N, Isom OW, Crystal RG, Rosengart TK. Mack CA, et al. Among authors: crystal rg. J Thorac Cardiovasc Surg. 1998 Jan;115(1):168-76; discussion 176-7. doi: 10.1016/s0022-5223(98)70455-6. J Thorac Cardiovasc Surg. 1998. PMID: 9451061 Free PMC article.
914 results