Sweeny DJ - Search Results

1

Stereospecific synthesis of a GS 4104 metabolite: determination of absolute stereochemistry and influenza neuraminidase inhibitory activity.

Lew W, Escarpe PA, Mendel DB, Sweeny DJ, Kim CU. Lew W, et al. Among authors: sweeny dj. Bioorg Med Chem Lett. 1999 Oct 4;9(19):2811-4. doi: 10.1016/s0960-894x(99)00479-5. Bioorg Med Chem Lett. 1999. PMID: 10522696

2

Metabolism of the influenza neuraminidase inhibitor prodrug oseltamivir in the rat.

Sweeny DJ, Lynch G, Bidgood AM, Lew W, Wang KY, Cundy KC. Sweeny DJ, et al. Drug Metab Dispos. 2000 Jul;28(7):737-41. Drug Metab Dispos. 2000. PMID: 10859145

3

Metabolism of fostamatinib, the oral methylene phosphate prodrug of the spleen tyrosine kinase inhibitor R406 in humans: contribution of hepatic and gut bacterial processes to the overall biotransformation.

Sweeny DJ, Li W, Clough J, Bhamidipati S, Singh R, Park G, Baluom M, Grossbard E, Lau DT. Sweeny DJ, et al. Drug Metab Dispos. 2010 Jul;38(7):1166-76. doi: 10.1124/dmd.110.032151. Epub 2010 Apr 6. Drug Metab Dispos. 2010. PMID: 20371637

4

Sulfation of acetaminophen in isolated rat hepatocytes. Relationship to sulfate ion concentrations and intracellular levels of 3'-phosphoadenosine-5'-phosphosulfate.

Sweeny DJ, Reinke LA. Sweeny DJ, et al. Drug Metab Dispos. 1988 Sep-Oct;16(5):712-5. Drug Metab Dispos. 1988. PMID: 2906595

5

Stereoselective glucuronidation of zileuton isomers by human hepatic microsomes.

Sweeny DJ, Nellans HN. Sweeny DJ, et al. Drug Metab Dispos. 1995 Jan;23(1):149-53. Drug Metab Dispos. 1995. PMID: 7720519

6

Structure activity relationships leading to the identification of the indirect activator of AMPK, R419.

Shaw SJ, Goff DA, Carroll DC, Singh R, Sweeny DJ, Park G, Jenkins Y, Markovtsov V, Sun TQ, Issakani SD, Hitoshi Y, Payan DG. Shaw SJ, et al. Among authors: sweeny dj. Bioorg Med Chem. 2022 Oct 1;71:116951. doi: 10.1016/j.bmc.2022.116951. Epub 2022 Aug 1. Bioorg Med Chem. 2022. PMID: 35973281

7

Glucuronidation of zileuton (A-64077) by human hepatic microsomes.

Sweeny DJ, Bouska J, Machinist J, Bell R, Carter G, Cepa S, Nellans HN. Sweeny DJ, et al. Drug Metab Dispos. 1992 Mar-Apr;20(2):328-9. Drug Metab Dispos. 1992. PMID: 1352229 No abstract available.

8

Metabolism of acetaminophen in hepatocytes isolated from mice and rats of various ages.

Sweeny DJ, Weiner M. Sweeny DJ, et al. Drug Metab Dispos. 1985 May-Jun;13(3):377-9. Drug Metab Dispos. 1985. PMID: 2862001 No abstract available.

9

Inhibition of glucuronidation and sulfation by dibutyryl cyclic AMP in isolated rat hepatocytes.

Shipley LA, Eacho PI, Sweeny DJ, Weiner M. Shipley LA, et al. Among authors: sweeny dj. Drug Metab Dispos. 1986 Sep-Oct;14(5):526-31. Drug Metab Dispos. 1986. PMID: 2876857

10

Effects of CYP3A4 Inhibitors Ketoconazole and Verapamil and the CYP3A4 Inducer Rifampicin on the Pharmacokinetic Parameters of Fostamatinib: Results from In Vitro and Phase I Clinical Studies.

Martin P, Gillen M, Millson D, Oliver S, Brealey C, Grossbard EB, Baluom M, Lau D, Sweeny D, Mant T, Craven K. Martin P, et al. Drugs R D. 2016 Mar;16(1):81-92. doi: 10.1007/s40268-015-0118-4. Drugs R D. 2016. PMID: 26739683 Free PMC article. Clinical Trial.

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