Yoshinari T - Search Results

1

Mode of action of a new indolocarbazole anticancer agent, J-107088, targeting topoisomerase I.

Yoshinari T, Ohkubo M, Fukasawa K, Egashira S, Hara Y, Matsumoto M, Nakai K, Arakawa H, Morishima H, Nishimura S. Yoshinari T, et al. Cancer Res. 1999 Sep 1;59(17):4271-5. Cancer Res. 1999. PMID: 10485471

2

Novel antitumor indolocarbazole compound 6-N-formylamino-12,13-dihydro-1,11- dihydroxy-13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo[3,4- c]carbazole-5,7(6H)-dione (NB-506): induction of topoisomerase I-mediated DNA cleavage and mechanisms of cell line-selective cytotoxicity.

Yoshinari T, Matsumoto M, Arakawa H, Okada H, Noguchi K, Suda H, Okura A, Nishimura S. Yoshinari T, et al. Cancer Res. 1995 Mar 15;55(6):1310-5. Cancer Res. 1995. PMID: 7882328

3

Novel indolocarbazole compound 6-N-formylamino-12,13-dihydro-1,11-dihydroxy- 13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo-[3,4-c]carbazole- 5,7(6H)-dione (NB-506): its potent antitumor activities in mice.

Arakawa H, Iguchi T, Morita M, Yoshinari T, Kojiri K, Suda H, Okura A, Nishimura S. Arakawa H, et al. Among authors: yoshinari t. Cancer Res. 1995 Mar 15;55(6):1316-20. Cancer Res. 1995. PMID: 7882329

4

ED-110, a novel indolocarbazole, prevents the growth of experimental tumors in mice.

Arakawa H, Iguchi T, Yoshinari T, Kojiri K, Suda H, Okura A. Arakawa H, et al. Among authors: yoshinari t. Jpn J Cancer Res. 1993 May;84(5):574-81. doi: 10.1111/j.1349-7006.1993.tb00178.x. Jpn J Cancer Res. 1993. PMID: 8320174 Free PMC article.

5

Induction of topoisomerase I-mediated DNA cleavage by a new indolocarbazole, ED-110.

Yoshinari T, Yamada A, Uemura D, Nomura K, Arakawa H, Kojiri K, Yoshida E, Suda H, Okura A. Yoshinari T, et al. Cancer Res. 1993 Feb 1;53(3):490-4. Cancer Res. 1993. PMID: 8381047

6

Sequence-selective DNA cleavage by a topoisomerase I poison, NB-506.

Fukasawa K, Komatani H, Hara Y, Suda H, Okura A, Nishimura S, Yoshinari T. Fukasawa K, et al. Among authors: yoshinari t. Int J Cancer. 1998 Jan 5;75(1):145-50. doi: 10.1002/(sici)1097-0215(19980105)75:1<145::aid-ijc22>3.0.co;2-e. Int J Cancer. 1998. PMID: 9426703

7

Synthesis and biological activities of topoisomerase I inhibitors, 6-N-amino analogues of NB-506.

Ohkubo M, Kojiri K, Kondo H, Tanaka S, Kawamoto H, Nishimura T, Nishimura I, Yoshinari T, Arakawa H, Suda H, Morishima H, Nishimura S. Ohkubo M, et al. Among authors: yoshinari t. Bioorg Med Chem Lett. 1999 May 3;9(9):1219-24. doi: 10.1016/s0960-894x(99)00188-2. Bioorg Med Chem Lett. 1999. PMID: 10340602

8

A new mechanism of acquisition of drug resistance by partial duplication of topoisomerase I.

Komatani H, Morita M, Sakaizumi N, Fukasawa K, Yoshida E, Okura A, Yoshinari T, Nishimura S. Komatani H, et al. Among authors: yoshinari t. Cancer Res. 1999 Jun 1;59(11):2701-8. Cancer Res. 1999. PMID: 10363995

9

Intercalation into DNA is not required for inhibition of topoisomerase I by indolocarbazole antitumor agents.

Bailly C, Dassonneville L, Colson P, Houssier C, Fukasawa K, Nishimura S, Yoshinari T. Bailly C, et al. Among authors: yoshinari t. Cancer Res. 1999 Jun 15;59(12):2853-60. Cancer Res. 1999. PMID: 10383146

10

Synthesis and biological activities of NB-506 analogues modified at the glucose group.

Ohkubo M, Nishimura T, Kawamoto H, Nakano M, Honma T, Yoshinari T, Arakawa H, Suda H, Morishima H, Nishimura S. Ohkubo M, et al. Among authors: yoshinari t. Bioorg Med Chem Lett. 2000 Mar 6;10(5):419-22. doi: 10.1016/s0960-894x(00)00004-4. Bioorg Med Chem Lett. 2000. PMID: 10743939

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