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Sulfonamidopyrrolidinone factor Xa inhibitors: potency and selectivity enhancements via P-1 and P-4 optimization.
J Med Chem. 1999 Sep 9;42(18):3572-87. doi: 10.1021/jm990041+.
J Med Chem. 1999.
PMID: 10479289
Design and structure-activity relationships of potent and selective inhibitors of blood coagulation factor Xa.
Ewing WR, Becker MR, Manetta VE, Davis RS, Pauls HW, Mason H, Choi-Sledeski YM, Green D, Cha D, Spada AP, Cheney DL, Mason JS, Maignan S, Guilloteau JP, Brown K, Colussi D, Bentley R, Bostwick J, Kasiewski CJ, Morgan SR, Leadley RJ, Dunwiddie CT, Perrone MH, Chu V.
Ewing WR, et al. Among authors: manetta ve.
J Med Chem. 1999 Sep 9;42(18):3557-71. doi: 10.1021/jm990040h.
J Med Chem. 1999.
PMID: 10479288
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