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Phase I trial of combined treatment with ch14.18 and R24 monoclonal antibodies and interleukin-2 for patients with melanoma or sarcoma.
Choi BS, Sondel PM, Hank JA, Schalch H, Gan J, King DM, Kendra K, Mahvi D, Lee LY, Kim K, Albertini MR. Choi BS, et al. Among authors: gan j. Cancer Immunol Immunother. 2006 Jul;55(7):761-74. doi: 10.1007/s00262-005-0069-7. Epub 2005 Sep 27. Cancer Immunol Immunother. 2006. PMID: 16187086 Free PMC article. Clinical Trial.
Intratumoral treatment of smaller mouse neuroblastoma tumors with a recombinant protein consisting of IL-2 linked to the hu14.18 antibody increases intratumoral CD8+ T and NK cells and improves survival.
Yang RK, Kalogriopoulos NA, Rakhmilevich AL, Ranheim EA, Seo S, Kim K, Alderson KL, Gan J, Reisfeld RA, Gillies SD, Hank JA, Sondel PM. Yang RK, et al. Among authors: gan j. Cancer Immunol Immunother. 2013 Aug;62(8):1303-13. doi: 10.1007/s00262-013-1430-x. Epub 2013 May 10. Cancer Immunol Immunother. 2013. PMID: 23661160 Free PMC article.
A phase I/IB trial of murine monoclonal anti-GD2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma: a report of the Children's Cancer Group.
Frost JD, Hank JA, Reaman GH, Frierdich S, Seeger RC, Gan J, Anderson PM, Ettinger LJ, Cairo MS, Blazar BR, Krailo MD, Matthay KK, Reisfeld RA, Sondel PM. Frost JD, et al. Among authors: gan j. Cancer. 1997 Jul 15;80(2):317-33. doi: 10.1002/(sici)1097-0142(19970715)80:2<317::aid-cncr21>3.0.co;2-w. Cancer. 1997. PMID: 9217046 Clinical Trial.
Treatment of neuroblastoma patients with antiganglioside GD2 antibody plus interleukin-2 induces antibody-dependent cellular cytotoxicity against neuroblastoma detected in vitro.
Hank JA, Surfus J, Gan J, Chew TL, Hong R, Tans K, Reisfeld R, Seeger RC, Reynolds CP, Bauer M, et al. Hank JA, et al. Among authors: gan j. J Immunother Emphasis Tumor Immunol. 1994 Jan;15(1):29-37. doi: 10.1097/00002371-199401000-00004. J Immunother Emphasis Tumor Immunol. 1994. PMID: 8110728
2,181 results