Nichols DE - Search Results

1

Quantitative structure-activity relationship modeling of dopamine D(1) antagonists using comparative molecular field analysis, genetic algorithms-partial least-squares, and K nearest neighbor methods.

Hoffman B, Cho SJ, Zheng W, Wyrick S, Nichols DE, Mailman RB, Tropsha A. Hoffman B, et al. Among authors: nichols de. J Med Chem. 1999 Aug 26;42(17):3217-26. doi: 10.1021/jm980415j. J Med Chem. 1999. PMID: 10464009

2

Dihydrexidine, a novel full efficacy D1 dopamine receptor agonist.

Mottola DM, Brewster WK, Cook LL, Nichols DE, Mailman RB. Mottola DM, et al. Among authors: nichols de. J Pharmacol Exp Ther. 1992 Jul;262(1):383-93. J Pharmacol Exp Ther. 1992. PMID: 1352553

3

Benzofuran bioisosteres of hallucinogenic tryptamines.

Tomaszewski Z, Johnson MP, Huang X, Nichols DE. Tomaszewski Z, et al. Among authors: nichols de. J Med Chem. 1992 May 29;35(11):2061-4. doi: 10.1021/jm00089a017. J Med Chem. 1992. PMID: 1534585

4

Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: similarities to 3,4-(methylenedioxy)methamphetamine (MDMA).

Johnson MP, Frescas SP, Oberlender R, Nichols DE. Johnson MP, et al. Among authors: nichols de. J Med Chem. 1991 May;34(5):1662-8. doi: 10.1021/jm00109a020. J Med Chem. 1991. PMID: 1674539

5

Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-induced parkinsonism in monkeys.

Taylor JR, Lawrence MS, Redmond DE Jr, Elsworth JD, Roth RH, Nichols DE, Mailman RB. Taylor JR, et al. Among authors: nichols de. Eur J Pharmacol. 1991 Jul 9;199(3):389-91. doi: 10.1016/0014-2999(91)90508-n. Eur J Pharmacol. 1991. PMID: 1680717 Free article. No abstract available.

6

Guanine nucleotide binding proteins and the regulation of cyclic AMP synthesis in NS20Y neuroblastoma cells: role of D1 dopamine and muscarinic receptors.

Lovenberg TW, Nichols DE, Nestler EJ, Roth RH, Mailman RB. Lovenberg TW, et al. Among authors: nichols de. Brain Res. 1991 Aug 9;556(1):101-7. doi: 10.1016/0006-8993(91)90552-7. Brain Res. 1991. PMID: 1682005

7

D1 and D2 dopamine receptors independently regulate spontaneous blink rate in the vervet monkey.

Elsworth JD, Lawrence MS, Roth RH, Taylor JR, Mailman RB, Nichols DE, Lewis MH, Redmond DE Jr. Elsworth JD, et al. Among authors: nichols de. J Pharmacol Exp Ther. 1991 Nov;259(2):595-600. J Pharmacol Exp Ther. 1991. PMID: 1682479

8

Behavioral effects in the rat of dihydrexidine, a high-potency, full-efficacy D1 dopamine receptor agonist.

Darney KJ Jr, Lewis MH, Brewster WK, Nichols DE, Mailman RB. Darney KJ Jr, et al. Among authors: nichols de. Neuropsychopharmacology. 1991 Nov;5(3):187-95. Neuropsychopharmacology. 1991. PMID: 1684499

9

D1 dopamine receptors of NS20Y neuroblastoma cells are functionally similar to rat striatal D1 receptors.

Lovenberg TW, Roth RH, Nichols DE, Mailman RB. Lovenberg TW, et al. Among authors: nichols de. J Neurochem. 1991 Nov;57(5):1563-9. doi: 10.1111/j.1471-4159.1991.tb06352.x. J Neurochem. 1991. PMID: 1717649

10

Stereoselective LSD-like activity in d-lysergic acid amides of (R)- and (S)-2-aminobutane.

Oberlender R, Pfaff RC, Johnson MP, Huang XM, Nichols DE. Oberlender R, et al. Among authors: nichols de. J Med Chem. 1992 Jan 24;35(2):203-11. doi: 10.1021/jm00080a001. J Med Chem. 1992. PMID: 1732537

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