Brown KW - Search Results

1

Transactivation of the WT1 antisense promoter is unique to the WT1[+/-] isoform.

Moorwood K, Salpekar A, Ivins SM, Hall J, Powlesland RM, Brown KW, Malik K. Moorwood K, et al. Among authors: brown kw. FEBS Lett. 1999 Jul 30;456(1):131-6. doi: 10.1016/s0014-5793(99)00944-8. FEBS Lett. 1999. PMID: 10452544 Free article.

2

Identification of an antisense WT1 promoter in intron 1: implications for WT1 gene regulation.

Malik KT, Wallace JI, Ivins SM, Brown KW. Malik KT, et al. Among authors: brown kw. Oncogene. 1995 Oct 19;11(8):1589-95. Oncogene. 1995. PMID: 7478583

3

Autoregulation of the human WT1 gene promoter.

Malik KT, Poirier V, Ivins SM, Brown KW. Malik KT, et al. Among authors: brown kw. FEBS Lett. 1994 Jul 25;349(1):75-8. doi: 10.1016/0014-5793(94)00642-3. FEBS Lett. 1994. PMID: 8045305 Free article.

4

Antisense WT1 transcription parallels sense mRNA and protein expression in fetal kidney and can elevate protein levels in vitro.

Moorwood K, Charles AK, Salpekar A, Wallace JI, Brown KW, Malik K. Moorwood K, et al. Among authors: brown kw. J Pathol. 1998 Aug;185(4):352-9. doi: 10.1002/(SICI)1096-9896(199808)185:4<352::AID-PATH119>3.0.CO;2-#. J Pathol. 1998. PMID: 9828833

5

Identification of differential methylation of the WT1 antisense regulatory region and relaxation of imprinting in Wilms' tumor.

Malik K, Salpekar A, Hancock A, Moorwood K, Jackson S, Charles A, Brown KW. Malik K, et al. Among authors: brown kw. Cancer Res. 2000 May 1;60(9):2356-60. Cancer Res. 2000. PMID: 10811108

6

Genomic imprinting at the WT1 gene involves a novel coding transcript (AWT1) that shows deregulation in Wilms' tumours.

Dallosso AR, Hancock AL, Brown KW, Williams AC, Jackson S, Malik K. Dallosso AR, et al. Among authors: brown kw. Hum Mol Genet. 2004 Feb 15;13(4):405-15. doi: 10.1093/hmg/ddh038. Epub 2003 Dec 17. Hum Mol Genet. 2004. PMID: 14681303

7

A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis.

Hancock AL, Brown KW, Moorwood K, Moon H, Holmgren C, Mardikar SH, Dallosso AR, Klenova E, Loukinov D, Ohlsson R, Lobanenkov VV, Malik K. Hancock AL, et al. Among authors: brown kw. Hum Mol Genet. 2007 Feb 1;16(3):343-54. doi: 10.1093/hmg/ddl478. Epub 2007 Jan 8. Hum Mol Genet. 2007. PMID: 17210670

8

Alternately spliced WT1 antisense transcripts interact with WT1 sense RNA and show epigenetic and splicing defects in cancer.

Dallosso AR, Hancock AL, Malik S, Salpekar A, King-Underwood L, Pritchard-Jones K, Peters J, Moorwood K, Ward A, Malik KT, Brown KW. Dallosso AR, et al. Among authors: brown kw. RNA. 2007 Dec;13(12):2287-99. doi: 10.1261/rna.562907. Epub 2007 Oct 16. RNA. 2007. PMID: 17940140 Free PMC article.

9

Loss of heterozygosity at 7p in Wilms' tumour development.

Powlesland RM, Charles AK, Malik KT, Reynolds PA, Pires S, Boavida M, Brown KW. Powlesland RM, et al. Among authors: brown kw. Br J Cancer. 2000 Jan;82(2):323-9. doi: 10.1054/bjoc.1999.0922. Br J Cancer. 2000. PMID: 10646884 Free PMC article.

10

Epigenetic gene deregulation in cancer.

Malik K, Brown KW. Malik K, et al. Among authors: brown kw. Br J Cancer. 2000 Dec;83(12):1583-8. doi: 10.1054/bjoc.2000.1549. Br J Cancer. 2000. PMID: 11104550 Free PMC article. Review.

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