Antonini I - Search Results

1

2,3-Dihydro-1H,7H-pyrimido[5,6,1-de]acridine-1,3,7-trione derivatives, a class of cytotoxic agents active on multidrug-resistant cell lines: synthesis, biological evaluation, and structure-activity relationships.

Antonini I, Polucci P, Kelland LR, Menta E, Pescalli N, Martelli S. Antonini I, et al. J Med Chem. 1999 Jul 15;42(14):2535-41. doi: 10.1021/jm9805586. J Med Chem. 1999. PMID: 10411474

2

2,6-Di(omega-aminoalkyl)-2,5,6,7-tetrahydropyrazolo[3,4,5-mn]pyrimido[5,6,1-de]acridine-5,7-diones: novel, potent, cytotoxic, and DNA-binding agents.

Antonini I, Polucci P, Magnano A, Gatto B, Palumbo M, Menta E, Pescalli N, Martelli S. Antonini I, et al. J Med Chem. 2002 Jan 31;45(3):696-702. doi: 10.1021/jm011004x. J Med Chem. 2002. PMID: 11806721

3

Rational design, synthesis and biological evaluation of thiadiazinoacridines: a new class of antitumor agents.

Antonini I, Polucci P, Magnano A, Cacciamani D, Konieczny MT, Paradziej-Łukowicz J, Martelli S. Antonini I, et al. Bioorg Med Chem. 2003 Feb 6;11(3):399-405. doi: 10.1016/s0968-0896(02)00442-x. Bioorg Med Chem. 2003. PMID: 12517435

4

Design, synthesis, and biological properties of new bis(acridine-4-carboxamides) as anticancer agents.

Antonini I, Polucci P, Magnano A, Gatto B, Palumbo M, Menta E, Pescalli N, Martelli S. Antonini I, et al. J Med Chem. 2003 Jul 3;46(14):3109-15. doi: 10.1021/jm030820x. J Med Chem. 2003. PMID: 12825949

5

Rational design, synthesis, and biological evaluation of bis(pyrimido[5,6,1-de]acridines) and bis(pyrazolo[3,4,5-kl]acridine-5-carboxamides) as new anticancer agents.

Antonini I, Polucci P, Magnano A, Sparapani S, Martelli S. Antonini I, et al. J Med Chem. 2004 Oct 7;47(21):5244-50. doi: 10.1021/jm049706k. J Med Chem. 2004. PMID: 15456268

6

Heterocyclic quinones with potential antitumor activity. 2. Synthesis and antitumor activity of some benzimidazole-4,7-dione derivatives.

Antonini I, Claudi F, Cristalli G, Franchetti P, Grifantini M, Martelli S. Antonini I, et al. J Med Chem. 1988 Jan;31(1):260-4. doi: 10.1021/jm00396a041. J Med Chem. 1988. PMID: 3336025

7

Synthesis of (dialkylamino)alkyl-disubstituted pyrimido[5,6,1- de]acridines, a novel group of anticancer agents active on a multidrug resistant cell line.

Antonini I, Cola D, Polucci P, Bontemps-Gracz M, Borowski E, Martelli S. Antonini I, et al. J Med Chem. 1995 Aug 18;38(17):3282-6. doi: 10.1021/jm00017a013. J Med Chem. 1995. PMID: 7650682

8

Pyrimido [4,5,6-kl] acridines, a new class of potential anticancer agents. Synthesis and biological evaluation.

Antonini I, Polucci P, Cola D, Bontemps-Gracz M, Pescalli N, Menta E, Martelli S. Antonini I, et al. Anticancer Drug Des. 1996 Jun;11(4):339-49. Anticancer Drug Des. 1996. PMID: 8679056

9

Synthesis and biological evaluation of mono- and bis-[(alkylamino)alkylamino] substituted thienopyridopyridazines, a new class of potential antitumor agents.

Antonini I, Cola D, Polucci P, Palmieri GF, Martelli S, Jenkins TC. Antonini I, et al. Farmaco. 1996 Jan;51(1):41-7. Farmaco. 1996. PMID: 8721760

10

1-[(omega-aminoalkyl)amino]-4-[N-(omega-aminoalkyl)carbamoyl]-9-oxo-9, 10-dihydroacridines as intercalating cytotoxic agents: synthesis, DNA binding, and biological evaluation.

Antonini I, Polucci P, Jenkins TC, Kelland LR, Menta E, Pescalli N, Stefanska B, Mazerski J, Martelli S. Antonini I, et al. J Med Chem. 1997 Nov 7;40(23):3749-55. doi: 10.1021/jm970114u. J Med Chem. 1997. PMID: 9371240

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