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Toxicology and pharmacokinetics of DTGM, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor, in cynomolgus monkeys.
Hotchkiss CE, Hall PD, Cline JM, Willingham MC, Kreitman RJ, Gardin J, Latimer A, Ramage J, Feely T, DeLatte S, Tagge EP, Frankel AE. Hotchkiss CE, et al. Among authors: kreitman rj. Toxicol Appl Pharmacol. 1999 Jul 15;158(2):152-60. doi: 10.1006/taap.1999.8691. Toxicol Appl Pharmacol. 1999. PMID: 10406930
Antibody response to DT-GM, a novel fusion toxin consisting of a truncated diphtheria toxin (DT) linked to human granulocyte-macrophage colony stimulating factor (GM), during a phase I trial of patients with relapsed or refractory acute myeloid leukemia.
Hall PD, Virella G, Willoughby T, Atchley DH, Kreitman RJ, Frankel AE. Hall PD, et al. Among authors: kreitman rj. Clin Immunol. 2001 Aug;100(2):191-7. doi: 10.1006/clim.2001.5066. Clin Immunol. 2001. PMID: 11465948 Clinical Trial.
260 results