Rubin EM - Search Results

1

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

Hodgson JG, Agopyan N, Gutekunst CA, Leavitt BR, LePiane F, Singaraja R, Smith DJ, Bissada N, McCutcheon K, Nasir J, Jamot L, Li XJ, Stevens ME, Rosemond E, Roder JC, Phillips AG, Rubin EM, Hersch SM, Hayden MR. Hodgson JG, et al. Among authors: rubin em. Neuron. 1999 May;23(1):181-92. doi: 10.1016/s0896-6273(00)80764-3. Neuron. 1999. PMID: 10402204 Free article.

2

Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotype.

Hodgson JG, Smith DJ, McCutcheon K, Koide HB, Nishiyama K, Dinulos MB, Stevens ME, Bissada N, Nasir J, Kanazawa I, Disteche CM, Rubin EM, Hayden MR. Hodgson JG, et al. Among authors: rubin em. Hum Mol Genet. 1996 Dec;5(12):1875-85. doi: 10.1093/hmg/5.12.1875. Hum Mol Genet. 1996. PMID: 8968738

3

Atherosclerosis in mice: getting to the heart of a polygenic disorder.

Rubin EM, Smith DJ. Rubin EM, et al. Trends Genet. 1994 Jun;10(6):199-203. doi: 10.1016/0168-9525(94)90256-9. Trends Genet. 1994. PMID: 8073533 Review.

4

Functional screening and complex traits: human 21q22.2 sequences affecting learning in mice.

Smith DJ, Rubin EM. Smith DJ, et al. Among authors: rubin em. Hum Mol Genet. 1997;6(10):1729-33. doi: 10.1093/hmg/6.10.1729. Hum Mol Genet. 1997. PMID: 9300665 Review.

5

Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome.

Smith DJ, Stevens ME, Sudanagunta SP, Bronson RT, Makhinson M, Watabe AM, O'Dell TJ, Fung J, Weier HU, Cheng JF, Rubin EM. Smith DJ, et al. Among authors: rubin em. Nat Genet. 1997 May;16(1):28-36. doi: 10.1038/ng0597-28. Nat Genet. 1997. PMID: 9140392

6

Optimizing the mouse to sift sequence for function.

Rubin EM, Smith DJ. Rubin EM, et al. Trends Genet. 1997 Nov;13(11):423-6. doi: 10.1016/s0168-9525(97)01293-6. Trends Genet. 1997. PMID: 9385835 Review. No abstract available.

7

Construction of a panel of transgenic mice containing a contiguous 2-Mb set of YAC/P1 clones from human chromosome 21q22.2.

Smith DJ, Zhu Y, Zhang J, Cheng JF, Rubin EM. Smith DJ, et al. Among authors: rubin em. Genomics. 1995 Jun 10;27(3):425-34. doi: 10.1006/geno.1995.1073. Genomics. 1995. PMID: 7558023

8

The vibrator mutation causes neurodegeneration via reduced expression of PITP alpha: positional complementation cloning and extragenic suppression.

Hamilton BA, Smith DJ, Mueller KL, Kerrebrock AW, Bronson RT, van Berkel V, Daly MJ, Kruglyak L, Reeve MP, Nemhauser JL, Hawkins TL, Rubin EM, Lander ES. Hamilton BA, et al. Among authors: rubin em. Neuron. 1997 May;18(5):711-22. doi: 10.1016/s0896-6273(00)80312-8. Neuron. 1997. PMID: 9182797 Free article.

9

Functional screening of an asthma QTL in YAC transgenic mice.

Symula DJ, Frazer KA, Ueda Y, Denefle P, Stevens ME, Wang ZE, Locksley R, Rubin EM. Symula DJ, et al. Among authors: rubin em. Nat Genet. 1999 Oct;23(2):241-4. doi: 10.1038/13880. Nat Genet. 1999. PMID: 10508526

10

Apolipoprotein B RNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolism.

Morrison JR, Pászty C, Stevens ME, Hughes SD, Forte T, Scott J, Rubin EM. Morrison JR, et al. Among authors: rubin em. Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7154-9. doi: 10.1073/pnas.93.14.7154. Proc Natl Acad Sci U S A. 1996. PMID: 8692961 Free PMC article.

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