Cooney DA - Search Results

1

Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis.

Jayaram HN, Cooney DA, Grusch M, Krupitza G. Jayaram HN, et al. Among authors: cooney da. Curr Med Chem. 1999 Jul;6(7):561-74. Curr Med Chem. 1999. PMID: 10390601 Review.

2

Cytotoxicity and characterization of an active metabolite of benzamide riboside, a novel inhibitor of IMP dehydrogenase.

Gharehbaghi K, Paull KD, Kelley JA, Barchi JJ Jr, Marquez VE, Cooney DA, Monks A, Scudiero D, Krohn K, Jayaram HN. Gharehbaghi K, et al. Among authors: cooney da. Int J Cancer. 1994 Mar 15;56(6):892-9. doi: 10.1002/ijc.2910560623. Int J Cancer. 1994. PMID: 7907081

3

Comparison of biochemical parameters of benzamide riboside, a new inhibitor of IMP dehydrogenase, with tiazofurin and selenazofurin.

Gharehbaghi K, Sreenath A, Hao Z, Paull KD, Szekeres T, Cooney DA, Krohn K, Jayaram HN. Gharehbaghi K, et al. Among authors: cooney da. Biochem Pharmacol. 1994 Oct 7;48(7):1413-9. doi: 10.1016/0006-2952(94)90565-7. Biochem Pharmacol. 1994. PMID: 7945441

4

Biochemical consequences of resistance to a recently discovered IMP dehydrogenase inhibitor, benzamide riboside, in human myelogenous leukemia K562 cells.

Jayaram HN, O'Connor A, Grant MR, Yang H, Grieco PA, Cooney DA. Jayaram HN, et al. Among authors: cooney da. J Exp Ther Oncol. 1996 Sep;1(5):278-85. J Exp Ther Oncol. 1996. PMID: 9414415

5

Cytotoxicity of tiazofurin and its arabinose and xylose analogues in K562 cells.

Zhen W, Jayaram HN, Marquez VE, Goldstein BM, Cooney DA, Weber G. Zhen W, et al. Among authors: cooney da. Biochem Biophys Res Commun. 1991 Oct 31;180(2):933-8. doi: 10.1016/s0006-291x(05)81155-6. Biochem Biophys Res Commun. 1991. PMID: 1683233

6

Ribavirin, tiazofurin, and selenazofurin: mononucleotides and nicotinamide adenine dinucleotide analogues. Synthesis, structure, and interactions with IMP dehydrogenase.

Gebeyehu G, Marquez VE, Van Cott A, Cooney DA, Kelley JA, Jayaram HN, Ahluwalia GS, Dion RL, Wilson YA, Johns DG. Gebeyehu G, et al. Among authors: cooney da. J Med Chem. 1985 Jan;28(1):99-105. doi: 10.1021/jm00379a018. J Med Chem. 1985. PMID: 2856943

7

Synthesis of thiazole-4-carboxamide adenine dinucleotide. A powerful inhibitor of IMP dehydrogenase.

Gebeyehu G, Marquez VE, Kelley JA, Cooney DA, Jayaram HN, Johns DG. Gebeyehu G, et al. Among authors: cooney da. J Med Chem. 1983 Jun;26(6):922-5. doi: 10.1021/jm00360a025. J Med Chem. 1983. PMID: 6133956

8

Relationships between the cytotoxicity of tiazofurin and its metabolism by cultured human lung cancer cells.

Carney DN, Ahluwalia GS, Jayaram HN, Cooney DA, Johns DG. Carney DN, et al. Among authors: cooney da. J Clin Invest. 1985 Jan;75(1):175-82. doi: 10.1172/JCI111671. J Clin Invest. 1985. PMID: 2856924 Free PMC article.

9

Studies on the mechanism of action of tiazofurin metabolism to an analog of NAD with potent IMP dehydrogenase-inhibitory activity.

Cooney DA, Jayaram HN, Glazer RI, Kelley JA, Marquez VE, Gebeyehu G, Van Cott AC, Zwelling LA, Johns DG. Cooney DA, et al. Adv Enzyme Regul. 1983;21:271-303. doi: 10.1016/0065-2571(83)90019-5. Adv Enzyme Regul. 1983. PMID: 6152729

10

Studies on the mechanism of action of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide). VI. Biochemical and pharmacological studies on the degradation of thiazole-4-carboxamide adenine dinucleotide (TAD).

Ahluwalia GS, Cooney DA, Marquez VE, Jayaram HN, Johns DG. Ahluwalia GS, et al. Among authors: cooney da. Biochem Pharmacol. 1986 Nov 1;35(21):3783-90. doi: 10.1016/0006-2952(86)90665-9. Biochem Pharmacol. 1986. PMID: 2877671

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