Hoelzer D - Search Results

1

PIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemia.

Sternsdorf T, Puccetti E, Jensen K, Hoelzer D, Will H, Ottmann OG, Ruthardt M. Sternsdorf T, et al. Among authors: hoelzer d. Mol Cell Biol. 1999 Jul;19(7):5170-8. doi: 10.1128/MCB.19.7.5170. Mol Cell Biol. 1999. PMID: 10373566 Free PMC article.

2

BCR-ABL mediates arsenic trioxide-induced apoptosis independently of its aberrant kinase activity.

Puccetti E, Güller S, Orleth A, Brüggenolte N, Hoelzer D, Ottmann OG, Ruthardt M. Puccetti E, et al. Among authors: hoelzer d. Cancer Res. 2000 Jul 1;60(13):3409-13. Cancer Res. 2000. PMID: 10910048

3

Leukemia-associated translocation products able to activate RAS modify PML and render cells sensitive to arsenic-induced apoptosis.

Puccetti E, Beissert T, Güller S, Li JE, Hoelzer D, Ottmann OG, Ruthardt M. Puccetti E, et al. Among authors: hoelzer d. Oncogene. 2003 Oct 9;22(44):6900-8. doi: 10.1038/sj.onc.1206747. Oncogene. 2003. PMID: 14534537

4

Gamma-catenin contributes to leukemogenesis induced by AML-associated translocation products by increasing the self-renewal of very primitive progenitor cells.

Zheng X, Beissert T, Kukoc-Zivojnov N, Puccetti E, Altschmied J, Strolz C, Boehrer S, Gul H, Schneider O, Ottmann OG, Hoelzer D, Henschler R, Ruthardt M. Zheng X, et al. Among authors: hoelzer d. Blood. 2004 May 1;103(9):3535-43. doi: 10.1182/blood-2003-09-3335. Epub 2004 Jan 22. Blood. 2004. PMID: 14739224 Free article.

5

Arsenic but not all-trans retinoic acid overcomes the aberrant stem cell capacity of PML/RARalpha-positive leukemic stem cells.

Zheng X, Seshire A, Rüster B, Bug G, Beissert T, Puccetti E, Hoelzer D, Henschler R, Ruthardt M. Zheng X, et al. Among authors: hoelzer d. Haematologica. 2007 Mar;92(3):323-31. doi: 10.3324/haematol.10541. Haematologica. 2007. PMID: 17339181 Free article.

6

AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.

Puccetti E, Obradovic D, Beissert T, Bianchini A, Washburn B, Chiaradonna F, Boehrer S, Hoelzer D, Ottmann OG, Pelicci PG, Nervi C, Ruthardt M. Puccetti E, et al. Among authors: hoelzer d. Cancer Res. 2002 Dec 1;62(23):7050-8. Cancer Res. 2002. PMID: 12460926

7

Down-stream regions of the POZ-domain influence the interaction of the t(11;17)-associated PLZF/RARalpha fusion protein with the histone-deacetylase recruiting co-repressor complex.

Puccetti E, Sennewald B, Fosca-Ferrara F, Boehrer S, Bianchini A, Hoelzer D, Ottmann OG, Nervi C, Ruthardt M. Puccetti E, et al. Among authors: hoelzer d. Hematol J. 2001;2(6):385-92. doi: 10.1038/sj.thj.6200138. Hematol J. 2001. PMID: 11920278

8

Targeting of the N-terminal coiled coil oligomerization interface of BCR interferes with the transformation potential of BCR-ABL and increases sensitivity to STI571.

Beissert T, Puccetti E, Bianchini A, Güller S, Boehrer S, Hoelzer D, Ottmann OG, Nervi C, Ruthardt M. Beissert T, et al. Among authors: hoelzer d. Blood. 2003 Oct 15;102(8):2985-93. doi: 10.1182/blood-2003-03-0811. Epub 2003 Jun 26. Blood. 2003. PMID: 12829585 Free article.

9

The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha.

Puccetti E, Zheng X, Brambilla D, Seshire A, Beissert T, Boehrer S, Nürnberger H, Hoelzer D, Ottmann OG, Nervi C, Ruthardt M. Puccetti E, et al. Among authors: hoelzer d. Cancer Res. 2005 Jul 15;65(14):6080-8. doi: 10.1158/0008-5472.CAN-04-3631. Cancer Res. 2005. PMID: 16024608

10

In lymphatic cells par-4 sensitizes to apoptosis by down-regulating bcl-2 and promoting disruption of mitochondrial membrane potential and caspase activation.

Boehrer S, Chow KU, Beske F, Kukoc-Zivojnov N, Puccetti E, Ruthardt M, Baum C, Rangnekar VM, Hoelzer D, Mitrou PS, Weidmann E. Boehrer S, et al. Among authors: hoelzer d. Cancer Res. 2002 Mar 15;62(6):1768-75. Cancer Res. 2002. PMID: 11912153

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