Witherington C - Search Results

1

Suppression of smooth muscle cell proliferation by a c-myc RNA-cleaving deoxyribozyme.

Sun LQ, Cairns MJ, Gerlach WL, Witherington C, Wang L, King A. Sun LQ, et al. Among authors: witherington c. J Biol Chem. 1999 Jun 11;274(24):17236-41. doi: 10.1074/jbc.274.24.17236. J Biol Chem. 1999. PMID: 10358082 Free article.

2

Target site selection for an RNA-cleaving catalytic DNA.

Cairns MJ, Hopkins TM, Witherington C, Wang L, Sun LQ. Cairns MJ, et al. Among authors: witherington c. Nat Biotechnol. 1999 May;17(5):480-6. doi: 10.1038/8658. Nat Biotechnol. 1999. PMID: 10331809

3

The influence of arm length asymmetry and base substitution on the activity of the 10-23 DNA enzyme.

Cairns MJ, Hopkins TM, Witherington C, Sun LQ. Cairns MJ, et al. Among authors: witherington c. Antisense Nucleic Acid Drug Dev. 2000 Oct;10(5):323-32. doi: 10.1089/oli.1.2000.10.323. Antisense Nucleic Acid Drug Dev. 2000. PMID: 11079572

4

Ribozyme-mediated suppression of Moloney murine leukemia virus and human immunodeficiency virus type I replication in permissive cell lines.

Sun LQ, Warrilow D, Wang L, Witherington C, Macpherson J, Symonds G. Sun LQ, et al. Among authors: witherington c. Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):9715-9. doi: 10.1073/pnas.91.21.9715. Proc Natl Acad Sci U S A. 1994. PMID: 7937878 Free PMC article.

5

Preclinical characterization of an anti-tat ribozyme for therapeutic application.

Wang L, Witherington C, King A, Gerlach WL, Carr A, Penny R, Cooper D, Symonds G, Sun LQ. Wang L, et al. Among authors: witherington c. Hum Gene Ther. 1998 Jun 10;9(9):1283-91. doi: 10.1089/hum.1998.9.9-1283. Hum Gene Ther. 1998. PMID: 9650613

6

The DNAzymes Rs6, Dz13, and DzF have potent biologic effects independent of catalytic activity.

Rivory L, Tucker C, King A, Lai A, Goodchild A, Witherington C, Gozar MM, Birkett DJ. Rivory L, et al. Among authors: witherington c. Oligonucleotides. 2006 Winter;16(4):297-312. doi: 10.1089/oli.2006.16.297. Oligonucleotides. 2006. PMID: 17155906

7

Dz13, a DNAzyme targeting c-jun, induces off-target cytotoxicity in endothelial cells with features of nonapoptotic programmed cell death.

Gozar MM, Goodchild A, Passioura T, King A, Lai A, Witherington C, Rivory L. Gozar MM, et al. Among authors: witherington c. Oligonucleotides. 2008 Sep;18(3):257-68. doi: 10.1089/oli.2008.0139. Oligonucleotides. 2008. PMID: 18699742

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