Gerson SL - Search Results

1

O6-benzylguanine: a clinical trial establishing the biochemical modulatory dose in tumor tissue for alkyltransferase-directed DNA repair.

Spiro TP, Gerson SL, Liu L, Majka S, Haaga J, Hoppel CL, Ingalls ST, Pluda JM, Willson JK. Spiro TP, et al. Among authors: gerson sl. Cancer Res. 1999 May 15;59(10):2402-10. Cancer Res. 1999. PMID: 10344750 Clinical Trial.

2

Base excision repair as a therapeutic target in colon cancer.

Liu L, Nakatsuru Y, Gerson SL. Liu L, et al. Among authors: gerson sl. Clin Cancer Res. 2002 Sep;8(9):2985-91. Clin Cancer Res. 2002. PMID: 12231545

3

Targeted modulation of MGMT: clinical implications.

Liu L, Gerson SL. Liu L, et al. Among authors: gerson sl. Clin Cancer Res. 2006 Jan 15;12(2):328-31. doi: 10.1158/1078-0432.CCR-05-2543. Clin Cancer Res. 2006. PMID: 16428468 Review.

4

Chemotherapy-induced O(6)-benzylguanine-resistant alkyltransferase mutations in mismatch-deficient colon cancer.

Liu L, Schwartz S, Davis BM, Gerson SL. Liu L, et al. Among authors: gerson sl. Cancer Res. 2002 Jun 1;62(11):3070-6. Cancer Res. 2002. PMID: 12036916

5

Pharmacokinetics of O6-benzylguanine (NSC637037) and its metabolite, 8-oxo-O6-benzylguanine.

Tserng KY, Ingalls ST, Boczko EM, Spiro TP, Li X, Majka S, Gerson SL, Willson JK, Hoppel CL. Tserng KY, et al. Among authors: gerson sl. J Clin Pharmacol. 2003 Aug;43(8):881-93. doi: 10.1177/0091270003256060. J Clin Pharmacol. 2003. PMID: 12953345 Clinical Trial.

6

New cytotoxic agents for the treatment of metastatic malignant melanoma: temozolomide and related alkylating agents in combination with guanine analogues to abrogate drug resistance.

Spiro T, Liu L, Gerson S. Spiro T, et al. Forum (Genova). 2000 Jul-Sep;10(3):274-85. Forum (Genova). 2000. PMID: 11007934 Review.

7

Modulation of nitrosourea resistance in human colon cancer by O6-methylguanine.

Gerson SL, Berger NA, Arce C, Petzold SJ, Willson JK. Gerson SL, et al. Biochem Pharmacol. 1992 Mar 3;43(5):1101-7. doi: 10.1016/0006-2952(92)90618-s. Biochem Pharmacol. 1992. PMID: 1554383

8

O6-alkylguanine-DNA alkyltransferase. A target for the modulation of drug resistance.

Gerson SL, Willson JK. Gerson SL, et al. Hematol Oncol Clin North Am. 1995 Apr;9(2):431-50. Hematol Oncol Clin North Am. 1995. PMID: 7642472 Review.

9

Modulation of O6-alkylguanine alkyltransferase-directed DNA repair in metastatic colon cancers.

Willson JK, Haaga JR, Trey JE, Stellato TA, Gordon NH, Gerson SL. Willson JK, et al. Among authors: gerson sl. J Clin Oncol. 1995 Sep;13(9):2301-8. doi: 10.1200/JCO.1995.13.9.2301. J Clin Oncol. 1995. PMID: 7666087 Clinical Trial.

10

Rapid repair of O6-methylguanine-DNA adducts protects transgenic mice from N-methylnitrosourea-induced thymic lymphomas.

Liu L, Allay E, Dumenco LL, Gerson SL. Liu L, et al. Among authors: gerson sl. Cancer Res. 1994 Sep 1;54(17):4648-52. Cancer Res. 1994. PMID: 8062258

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