Brinkmann U - Search Results

1

Tissue-specific alternative splicing of the CSE1L/CAS (cellular apoptosis susceptibility) gene.

Brinkmann U, Brinkmann E, Bera TK, Wellmann A, Pastan I. Brinkmann U, et al. Among authors: brinkmann e. Genomics. 1999 May 15;58(1):41-9. doi: 10.1006/geno.1998.5700. Genomics. 1999. PMID: 10331944

2

Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1.

Brinkmann U, Brinkmann E, Gallo M, Pastan I. Brinkmann U, et al. Among authors: brinkmann e. Proc Natl Acad Sci U S A. 1995 Oct 24;92(22):10427-31. doi: 10.1073/pnas.92.22.10427. Proc Natl Acad Sci U S A. 1995. PMID: 7479798 Free PMC article.

3

Role of CAS, a human homologue to the yeast chromosome segregation gene CSE1, in toxin and tumor necrosis factor mediated apoptosis.

Brinkmann U, Brinkmann E, Gallo M, Scherf U, Pastan I. Brinkmann U, et al. Among authors: brinkmann e. Biochemistry. 1996 May 28;35(21):6891-9. doi: 10.1021/bi952829+. Biochemistry. 1996. PMID: 8639641

We have previously isolated by expression/selection cloning plasmids containing human cDNAs that rendered MCF-7 breast cancer cells resistant to immunotoxins, Pseudomonas exotoxin (PE), and diphtheria toxin (DT) [Brinkmann et al. (1995) Mol. Med. 1, 206-216]. Here we descr …

We have previously isolated by expression/selection cloning plasmids containing human cDNAs that rendered MCF-7 breast cancer cells resistan …

4

The human CAS (cellular apoptosis susceptibility) gene mapping on chromosome 20q13 is amplified in BT474 breast cancer cells and part of aberrant chromosomes in breast and colon cancer cell lines.

Brinkmann U, Gallo M, Polymeropoulos MH, Pastan I. Brinkmann U, et al. Genome Res. 1996 Mar;6(3):187-94. doi: 10.1101/gr.6.3.187. Genome Res. 1996. PMID: 8963895 Free article.

5

Localization of the cell proliferation and apoptosis-associated CAS protein in lymphoid neoplasms.

Wellmann A, Krenacs L, Fest T, Scherf U, Pastan I, Raffeld M, Brinkmann U. Wellmann A, et al. Among authors: brinkmann u. Am J Pathol. 1997 Jan;150(1):25-30. Am J Pathol. 1997. PMID: 9006318 Free PMC article.

6

Antisense inhibition of CAS, the human homologue of the yeast chromosome segregation gene CSE1, interferes with mitosis in HeLa cells.

Ogryzko VV, Brinkmann E, Howard BH, Pastan I, Brinkmann U. Ogryzko VV, et al. Among authors: brinkmann e, brinkmann u. Biochemistry. 1997 Aug 5;36(31):9493-500. doi: 10.1021/bi970236o. Biochemistry. 1997. PMID: 9235994

7

Cse1l is essential for early embryonic growth and development.

Bera TK, Bera J, Brinkmann U, Tessarollo L, Pastan I. Bera TK, et al. Among authors: brinkmann u. Mol Cell Biol. 2001 Oct;21(20):7020-4. doi: 10.1128/MCB.21.20.7020-7024.2001. Mol Cell Biol. 2001. PMID: 11564884 Free PMC article.

8

The human CAS protein which is homologous to the CSE1 yeast chromosome segregation gene product is associated with microtubules and mitotic spindle.

Scherf U, Pastan I, Willingham MC, Brinkmann U. Scherf U, et al. Among authors: brinkmann u. Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):2670-4. doi: 10.1073/pnas.93.7.2670. Proc Natl Acad Sci U S A. 1996. PMID: 8610099 Free PMC article.

9

The hCSE1/CAS protein is phosphorylated by HeLa extracts and MEK-1: MEK-1 phosphorylation may modulate the intracellular localization of CAS.

Scherf U, Kalab P, Dasso M, Pastan I, Brinkmann U. Scherf U, et al. Among authors: brinkmann u. Biochem Biophys Res Commun. 1998 Sep 29;250(3):623-8. doi: 10.1006/bbrc.1998.9367. Biochem Biophys Res Commun. 1998. PMID: 9784396

10

High expression of the proliferation and apoptosis associated CSE1L/CAS gene in hepatitis and liver neoplasms: correlation with tumor progression.

Wellmann A, Flemming P, Behrens P, Wuppermann K, Lang H, Oldhafer K, Pastan I, Brinkmann U. Wellmann A, et al. Among authors: brinkmann u. Int J Mol Med. 2001 May;7(5):489-94. doi: 10.3892/ijmm.7.5.489. Int J Mol Med. 2001. PMID: 11295109

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