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Rho family proteins and cell migration.
Ridley AJ, Allen WE, Peppelenbosch M, Jones GE. Ridley AJ, et al. Among authors: peppelenbosch m. Biochem Soc Symp. 1999;65:111-23. Biochem Soc Symp. 1999. PMID: 10320936 Review.
The ATG16L1 risk allele associated with Crohn's disease results in a Rac1-dependent defect in dendritic cell migration that is corrected by thiopurines.
Wildenberg ME, Koelink PJ, Diederen K, Te Velde AA, Wolfkamp SC, Nuij VJ, Peppelenbosch MP, Nobis M, Sansom OJ, Anderson KI, van der Woude CJ, D'Haens GR, van den Brink GR. Wildenberg ME, et al. Among authors: peppelenbosch mp. Mucosal Immunol. 2017 Mar;10(2):352-360. doi: 10.1038/mi.2016.65. Epub 2016 Jul 20. Mucosal Immunol. 2017. PMID: 27435106 Free article.
Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK.
Voorneveld PW, Kodach LL, Jacobs RJ, Liv N, Zonnevylle AC, Hoogenboom JP, Biemond I, Verspaget HW, Hommes DW, de Rooij K, van Noesel CJ, Morreau H, van Wezel T, Offerhaus GJ, van den Brink GR, Peppelenbosch MP, Ten Dijke P, Hardwick JC. Voorneveld PW, et al. Among authors: peppelenbosch mp. Gastroenterology. 2014 Jul;147(1):196-208.e13. doi: 10.1053/j.gastro.2014.03.052. Epub 2014 Apr 3. Gastroenterology. 2014. PMID: 24704720
560 results