Connolly PJ - Search Results

1

N-hydroxyurea and hydroxamic acid inhibitors of cyclooxygenase and 5-lipoxygenase.

Connolly PJ, Wetter SK, Beers KN, Hamel SC, Chen RH, Wachter MP, Ansell J, Singer MM, Steber M, Ritchie DM, Argentieri DC. Connolly PJ, et al. Bioorg Med Chem Lett. 1999 Apr 5;9(7):979-84. doi: 10.1016/s0960-894x(99)00117-1. Bioorg Med Chem Lett. 1999. PMID: 10230624

2

HMG-CoA reductase inhibitors: design, synthesis, and biological activity of tetrahydroindazole-substituted 3,5-dihydroxy-6-heptenoic acid sodium salts.

Connolly PJ, Westin CD, Loughney DA, Minor LK. Connolly PJ, et al. J Med Chem. 1993 Nov 12;36(23):3674-85. doi: 10.1021/jm00075a024. J Med Chem. 1993. PMID: 8246237

3

Synthesis and erythropoietin receptor binding affinities of N,N-disubstituted amino acids.

Connolly PJ, Wetter SK, Murray WV, Johnson DL, McMahon FJ, Farrell FX, Tullai J, Jolliffe LK. Connolly PJ, et al. Bioorg Med Chem Lett. 2000 Sep 4;10(17):1995-9. doi: 10.1016/s0960-894x(00)00399-1. Bioorg Med Chem Lett. 2000. PMID: 10987435

4

Synthesis and discovery of macrocyclic polyoxygenated bis-7-azaindolylmaleimides as a novel series of potent and highly selective glycogen synthase kinase-3beta inhibitors.

Kuo GH, Prouty C, DeAngelis A, Shen L, O'Neill DJ, Shah C, Connolly PJ, Murray WV, Conway BR, Cheung P, Westover L, Xu JZ, Look RA, Demarest KT, Emanuel S, Middleton SA, Jolliffe L, Beavers MP, Chen X. Kuo GH, et al. Among authors: connolly pj. J Med Chem. 2003 Sep 11;46(19):4021-31. doi: 10.1021/jm030115o. J Med Chem. 2003. PMID: 12954055

5

Synthesis and discovery of pyrazine-pyridine biheteroaryl as a novel series of potent vascular endothelial growth factor receptor-2 inhibitors.

Kuo GH, Wang A, Emanuel S, Deangelis A, Zhang R, Connolly PJ, Murray WV, Gruninger RH, Sechler J, Fuentes-Pesquera A, Johnson D, Middleton SA, Jolliffe L, Chen X. Kuo GH, et al. Among authors: connolly pj. J Med Chem. 2005 Mar 24;48(6):1886-900. doi: 10.1021/jm040099a. J Med Chem. 2005. PMID: 15771433

6

3-Acyl-2,6-diaminopyridines as cyclin-dependent kinase inhibitors: synthesis and biological evaluation.

Lin R, Lu Y, Wetter SK, Connolly PJ, Turchi IJ, Murray WV, Emanuel SL, Gruninger RH, Fuentes-Pesquera AR, Adams M, Pandey N, Moreno-Mazza S, Middleton SA, Jolliffe LK. Lin R, et al. Among authors: connolly pj. Bioorg Med Chem Lett. 2005 May 2;15(9):2221-4. doi: 10.1016/j.bmcl.2005.03.024. Bioorg Med Chem Lett. 2005. PMID: 15837297

7

1-Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent anticancer cyclin-dependent kinase inhibitors: synthesis and evaluation of biological activities.

Lin R, Connolly PJ, Huang S, Wetter SK, Lu Y, Murray WV, Emanuel SL, Gruninger RH, Fuentes-Pesquera AR, Rugg CA, Middleton SA, Jolliffe LK. Lin R, et al. Among authors: connolly pj. J Med Chem. 2005 Jun 30;48(13):4208-11. doi: 10.1021/jm050267e. J Med Chem. 2005. PMID: 15974571

8

Synthesis and identification of [1,3,5]triazine-pyridine biheteroaryl as a novel series of potent cyclin-dependent kinase inhibitors.

Kuo GH, Deangelis A, Emanuel S, Wang A, Zhang Y, Connolly PJ, Chen X, Gruninger RH, Rugg C, Fuentes-Pesquera A, Middleton SA, Jolliffe L, Murray WV. Kuo GH, et al. Among authors: connolly pj. J Med Chem. 2005 Jul 14;48(14):4535-46. doi: 10.1021/jm040214h. J Med Chem. 2005. PMID: 15999992

9

Synthesis and structure-activity relationships of pyrazine-pyridine biheteroaryls as novel, potent, and selective vascular endothelial growth factor receptor-2 inhibitors.

Kuo GH, Prouty C, Wang A, Emanuel S, Deangelis A, Zhang Y, Song F, Beall L, Connolly PJ, Karnachi P, Chen X, Gruninger RH, Sechler J, Fuentes-Pesquera A, Middleton SA, Jolliffe L, Murray WV. Kuo GH, et al. Among authors: connolly pj. J Med Chem. 2005 Jul 28;48(15):4892-909. doi: 10.1021/jm058205b. J Med Chem. 2005. PMID: 16033269

10

Preparation of 3-spirocyclic indolin-2-ones as ligands for the ORL-1 receptor.

Bignan GC, Battista K, Connolly PJ, Orsini MJ, Liu J, Middleton SA, Reitz AB. Bignan GC, et al. Among authors: connolly pj. Bioorg Med Chem Lett. 2005 Nov 15;15(22):5022-6. doi: 10.1016/j.bmcl.2005.08.009. Bioorg Med Chem Lett. 2005. PMID: 16153834

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