Wrighton SA - Search Results

1

Midazolam metabolism by modified Caco-2 monolayers: effects of extracellular protein binding.

Fisher JM, Wrighton SA, Calamia JC, Shen DD, Kunze KL, Thummel KE. Fisher JM, et al. Among authors: wrighton sa. J Pharmacol Exp Ther. 1999 May;289(2):1143-50. J Pharmacol Exp Ther. 1999. PMID: 10215698

2

First-pass midazolam metabolism catalyzed by 1alpha,25-dihydroxy vitamin D3-modified Caco-2 cell monolayers.

Fisher JM, Wrighton SA, Watkins PB, Schmiedlin-Ren P, Calamia JC, Shen DD, Kunze KL, Thummel KE. Fisher JM, et al. Among authors: wrighton sa. J Pharmacol Exp Ther. 1999 May;289(2):1134-42. J Pharmacol Exp Ther. 1999. PMID: 10215697

3

The human CYP3A subfamily: practical considerations.

Wrighton SA, Schuetz EG, Thummel KE, Shen DD, Korzekwa KR, Watkins PB. Wrighton SA, et al. Drug Metab Rev. 2000 Aug-Nov;32(3-4):339-61. doi: 10.1081/dmr-100102338. Drug Metab Rev. 2000. PMID: 11139133 Review. No abstract available.

4

Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank.

Fisher MB, Vandenbranden M, Findlay K, Burchell B, Thummel KE, Hall SD, Wrighton SA. Fisher MB, et al. Among authors: wrighton sa. Pharmacogenetics. 2000 Nov;10(8):727-39. doi: 10.1097/00008571-200011000-00007. Pharmacogenetics. 2000. PMID: 11186135

5

Molecular and physical mechanisms of first-pass extraction.

Hall SD, Thummel KE, Watkins PB, Lown KS, Benet LZ, Paine MF, Mayo RR, Turgeon DK, Bailey DG, Fontana RJ, Wrighton SA. Hall SD, et al. Among authors: wrighton sa. Drug Metab Dispos. 1999 Feb;27(2):161-6. Drug Metab Dispos. 1999. PMID: 9929497 Review.

6

Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test.

Lown KS, Kolars JC, Thummel KE, Barnett JL, Kunze KL, Wrighton SA, Watkins PB. Lown KS, et al. Among authors: wrighton sa. Drug Metab Dispos. 1994 Nov-Dec;22(6):947-55. Drug Metab Dispos. 1994. PMID: 7895614

7

Effect of fluoxetine, norfluoxetine, sertraline and desmethyl sertraline on human CYP3A catalyzed 1'-hydroxy midazolam formation in vitro.

Ring BJ, Binkley SN, Roskos L, Wrighton SA. Ring BJ, et al. Among authors: wrighton sa. J Pharmacol Exp Ther. 1995 Dec;275(3):1131-5. J Pharmacol Exp Ther. 1995. PMID: 8531073

8

Further characterization of the expression in liver and catalytic activity of CYP2B6.

Ekins S, Vandenbranden M, Ring BJ, Gillespie JS, Yang TJ, Gelboin HV, Wrighton SA. Ekins S, et al. Among authors: wrighton sa. J Pharmacol Exp Ther. 1998 Sep;286(3):1253-9. J Pharmacol Exp Ther. 1998. PMID: 9732386

9

Three- and four-dimensional quantitative structure activity relationship analyses of cytochrome P-450 3A4 inhibitors.

Ekins S, Bravi G, Binkley S, Gillespie JS, Ring BJ, Wikel JH, Wrighton SA. Ekins S, et al. Among authors: wrighton sa. J Pharmacol Exp Ther. 1999 Jul;290(1):429-38. J Pharmacol Exp Ther. 1999. PMID: 10381809

10

Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities.

Dantzig AH, Shepard RL, Law KL, Tabas L, Pratt S, Gillespie JS, Binkley SN, Kuhfeld MT, Starling JJ, Wrighton SA. Dantzig AH, et al. Among authors: wrighton sa. J Pharmacol Exp Ther. 1999 Aug;290(2):854-62. J Pharmacol Exp Ther. 1999. PMID: 10411602

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