Selkoe DJ - Search Results

1

Peptidomimetic probes and molecular modeling suggest that Alzheimer's gamma-secretase is an intramembrane-cleaving aspartyl protease.

Wolfe MS, Xia W, Moore CL, Leatherwood DD, Ostaszewski B, Rahmati T, Donkor IO, Selkoe DJ. Wolfe MS, et al. Among authors: selkoe dj. Biochemistry. 1999 Apr 13;38(15):4720-7. doi: 10.1021/bi982562p. Biochemistry. 1999. PMID: 10200159

2

Detection of distinct isoform patterns of the beta-amyloid precursor protein in human platelets and lymphocytes.

Schlossmacher MG, Ostaszewski BL, Hecker LI, Celi A, Haass C, Chin D, Lieberburg I, Furie BC, Furie B, Selkoe DJ. Schlossmacher MG, et al. Among authors: selkoe dj. Neurobiol Aging. 1992 May-Jun;13(3):421-34. doi: 10.1016/0197-4580(92)90117-g. Neurobiol Aging. 1992. PMID: 1625772

3

Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture.

Podlisny MB, Ostaszewski BL, Squazzo SL, Koo EH, Rydell RE, Teplow DB, Selkoe DJ. Podlisny MB, et al. Among authors: selkoe dj. J Biol Chem. 1995 Apr 21;270(16):9564-70. doi: 10.1074/jbc.270.16.9564. J Biol Chem. 1995. PMID: 7721886 Free article.

4

Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma.

Biere AL, Ostaszewski B, Stimson ER, Hyman BT, Maggio JE, Selkoe DJ. Biere AL, et al. Among authors: selkoe dj. J Biol Chem. 1996 Dec 20;271(51):32916-22. doi: 10.1074/jbc.271.51.32916. J Biol Chem. 1996. PMID: 8955133 Free article.

5

Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins.

Xia W, Zhang J, Kholodenko D, Citron M, Podlisny MB, Teplow DB, Haass C, Seubert P, Koo EH, Selkoe DJ. Xia W, et al. Among authors: selkoe dj. J Biol Chem. 1997 Mar 21;272(12):7977-82. doi: 10.1074/jbc.272.12.7977. J Biol Chem. 1997. PMID: 9065468 Free article.

6

Co-expression of beta-amyloid precursor protein (betaAPP) and apolipoprotein E in cell culture: analysis of betaAPP processing.

Biere AL, Ostaszewski B, Zhao H, Gillespie S, Younkin SG, Selkoe DJ. Biere AL, et al. Among authors: selkoe dj. Neurobiol Dis. 1995 Jun;2(3):177-87. doi: 10.1006/nbdi.1995.0019. Neurobiol Dis. 1995. PMID: 9174001

7

Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer disease.

Xia W, Zhang J, Perez R, Koo EH, Selkoe DJ. Xia W, et al. Among authors: selkoe dj. Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):8208-13. doi: 10.1073/pnas.94.15.8208. Proc Natl Acad Sci U S A. 1997. PMID: 9223340 Free PMC article.

8

A substrate-based difluoro ketone selectively inhibits Alzheimer's gamma-secretase activity.

Wolfe MS, Citron M, Diehl TS, Xia W, Donkor IO, Selkoe DJ. Wolfe MS, et al. Among authors: selkoe dj. J Med Chem. 1998 Jan 1;41(1):6-9. doi: 10.1021/jm970621b. J Med Chem. 1998. PMID: 9438016 No abstract available.

9

Oligomerization of endogenous and synthetic amyloid beta-protein at nanomolar levels in cell culture and stabilization of monomer by Congo red.

Podlisny MB, Walsh DM, Amarante P, Ostaszewski BL, Stimson ER, Maggio JE, Teplow DB, Selkoe DJ. Podlisny MB, et al. Among authors: selkoe dj. Biochemistry. 1998 Mar 17;37(11):3602-11. doi: 10.1021/bi972029u. Biochemistry. 1998. PMID: 9521679

10

Additive effects of PS1 and APP mutations on secretion of the 42-residue amyloid beta-protein.

Citron M, Eckman CB, Diehl TS, Corcoran C, Ostaszewski BL, Xia W, Levesque G, St George Hyslop P, Younkin SG, Selkoe DJ. Citron M, et al. Among authors: selkoe dj. Neurobiol Dis. 1998 Aug;5(2):107-16. doi: 10.1006/nbdi.1998.0183. Neurobiol Dis. 1998. PMID: 9746908

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