Patel S - Search Results

1

Synthesis and sar of 2- and 3-substituted 7-azaindoles as potential dopamine D4 ligands.

Curtis NR, Kulagowski JJ, Leeson PD, Ridgill MP, Emms F, Freedman SB, Patel S, Patel S. Curtis NR, et al. Among authors: patel s. Bioorg Med Chem Lett. 1999 Feb 22;9(4):585-8. doi: 10.1016/s0960-894x(99)00025-6. Bioorg Med Chem Lett. 1999. PMID: 10098669

2

Synthesis and muscarinic activities of 1,2,4-thiadiazoles.

MacLeod AM, Baker R, Freedman SB, Patel S, Merchant KJ, Roe M, Saunders J. MacLeod AM, et al. Among authors: patel s. J Med Chem. 1990 Jul;33(7):2052-9. doi: 10.1021/jm00169a041. J Med Chem. 1990. PMID: 2362286

3

Selective non-peptide ligands for an accommodating peptide receptor. Imidazobenzodiazepines as potent cholecystokinin type B receptor antagonists.

Bock MG, DiPardo RM, Newton RC, Bergman JM, Veber DF, Freedman SB, Smith AJ, Chapman KL, Patel S, Kemp JA, et al. Bock MG, et al. Among authors: patel s. Bioorg Med Chem. 1994 Sep;2(9):987-98. doi: 10.1016/s0968-0896(00)82047-7. Bioorg Med Chem. 1994. PMID: 7712133

4

3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor.

Kulagowski JJ, Broughton HB, Curtis NR, Mawer IM, Ridgill MP, Baker R, Emms F, Freedman SB, Marwood R, Patel S, Patel S, Ragan CI, Leeson PD. Kulagowski JJ, et al. Among authors: patel s. J Med Chem. 1996 May 10;39(10):1941-2. doi: 10.1021/jm9600712. J Med Chem. 1996. PMID: 8642550 No abstract available.

5

5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole: a potent, selective antagonist at human cloned dopamine D4 receptors.

Rowley M, Broughton HB, Collins I, Baker R, Emms F, Marwood R, Patel S, Patel S, Ragan CI, Freedman SB, Leeson PD. Rowley M, et al. Among authors: patel s. J Med Chem. 1996 May 10;39(10):1943-5. doi: 10.1021/jm960072u. J Med Chem. 1996. PMID: 8642551 No abstract available.

6

Identification and pharmacological characterization of [125I]L-750,667, a novel radioligand for the dopamine D4 receptor.

Patel S, Patel S, Marwood R, Emms F, Marston D, Leeson PD, Curtis NR, Kulagowski JJ, Freedman SB. Patel S, et al. Mol Pharmacol. 1996 Dec;50(6):1658-64. Mol Pharmacol. 1996. PMID: 8967990

7

Antagonism of the effects of (+)-PD 128907 on midbrain dopamine neurones in rat brain slices by a selective D2 receptor antagonist L-741,626.

Bowery BJ, Razzaque Z, Emms F, Patel S, Freedman S, Bristow L, Kulagowski J, Seabrook GR. Bowery BJ, et al. Among authors: patel s. Br J Pharmacol. 1996 Dec;119(7):1491-7. doi: 10.1111/j.1476-5381.1996.tb16063.x. Br J Pharmacol. 1996. PMID: 8968560 Free PMC article.

8

4-Heterocyclylpiperidines as selective high-affinity ligands at the human dopamine D4 receptor.

Rowley M, Collins I, Broughton HB, Davey WB, Baker R, Emms F, Marwood R, Patel S, Patel S, Ragan CI, Freedman SB, Ball R, Leeson PD. Rowley M, et al. Among authors: patel s. J Med Chem. 1997 Jul 18;40(15):2374-85. doi: 10.1021/jm970111h. J Med Chem. 1997. PMID: 9240352

9

Biological profile of L-745,870, a selective antagonist with high affinity for the dopamine D4 receptor.

Patel S, Freedman S, Chapman KL, Emms F, Fletcher AE, Knowles M, Marwood R, Mcallister G, Myers J, Curtis N, Kulagowski JJ, Leeson PD, Ridgill M, Graham M, Matheson S, Rathbone D, Watt AP, Bristow LJ, Rupniak NM, Baskin E, Lynch JJ, Ragan CI. Patel S, et al. J Pharmacol Exp Ther. 1997 Nov;283(2):636-47. J Pharmacol Exp Ther. 1997. PMID: 9353380

10

L-745,870, a subtype selective dopamine D4 receptor antagonist, does not exhibit a neuroleptic-like profile in rodent behavioral tests.

Bristow LJ, Collinson N, Cook GP, Curtis N, Freedman SB, Kulagowski JJ, Leeson PD, Patel S, Ragan CI, Ridgill M, Saywell KL, Tricklebank MD. Bristow LJ, et al. Among authors: patel s. J Pharmacol Exp Ther. 1997 Dec;283(3):1256-63. J Pharmacol Exp Ther. 1997. PMID: 9400001

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