Otto JC - Search Results

1

Cloning and characterization of a mammalian prenyl protein-specific protease.

Otto JC, Kim E, Young SG, Casey PJ. Otto JC, et al. J Biol Chem. 1999 Mar 26;274(13):8379-82. doi: 10.1074/jbc.274.13.8379. J Biol Chem. 1999. PMID: 10085068 Free article.

2

On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy.

Bergo MO, Lieu HD, Gavino BJ, Ambroziak P, Otto JC, Casey PJ, Walker QM, Young SG. Bergo MO, et al. Among authors: otto jc. J Biol Chem. 2004 Feb 6;279(6):4729-36. doi: 10.1074/jbc.M310081200. Epub 2003 Nov 18. J Biol Chem. 2004. PMID: 14625273 Free article.

3

The hepatitis delta virus large antigen is farnesylated both in vitro and in animal cells.

Otto JC, Casey PJ. Otto JC, et al. J Biol Chem. 1996 Mar 1;271(9):4569-72. doi: 10.1074/jbc.271.9.4569. J Biol Chem. 1996. PMID: 8617711 Free article.

4

Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells.

Kim E, Ambroziak P, Otto JC, Taylor B, Ashby M, Shannon K, Casey PJ, Young SG. Kim E, et al. Among authors: otto jc. J Biol Chem. 1999 Mar 26;274(13):8383-90. doi: 10.1074/jbc.274.13.8383. J Biol Chem. 1999. PMID: 10085069 Free article.

5

Targeted inactivation of the isoprenylcysteine carboxyl methyltransferase gene causes mislocalization of K-Ras in mammalian cells.

Bergo MO, Leung GK, Ambroziak P, Otto JC, Casey PJ, Young SG. Bergo MO, et al. Among authors: otto jc. J Biol Chem. 2000 Jun 9;275(23):17605-10. doi: 10.1074/jbc.C000079200. J Biol Chem. 2000. PMID: 10747846 Free article.

6

The C-terminal polylysine region and methylation of K-Ras are critical for the interaction between K-Ras and microtubules.

Chen Z, Otto JC, Bergo MO, Young SG, Casey PJ. Chen Z, et al. Among authors: otto jc. J Biol Chem. 2000 Dec 29;275(52):41251-7. doi: 10.1074/jbc.M006687200. J Biol Chem. 2000. PMID: 11007785 Free article.

7

Isoprenylcysteine carboxyl methyltransferase deficiency in mice.

Bergo MO, Leung GK, Ambroziak P, Otto JC, Casey PJ, Gomes AQ, Seabra MC, Young SG. Bergo MO, et al. Among authors: otto jc. J Biol Chem. 2001 Feb 23;276(8):5841-5. doi: 10.1074/jbc.C000831200. Epub 2000 Dec 19. J Biol Chem. 2001. PMID: 11121396 Free article.

8

Time-dependent inhibition of isoprenylcysteine carboxyl methyltransferase by indole-based small molecules.

Baron RA, Peterson YK, Otto JC, Rudolph J, Casey PJ. Baron RA, et al. Among authors: otto jc. Biochemistry. 2007 Jan 16;46(2):554-60. doi: 10.1021/bi060344n. Biochemistry. 2007. PMID: 17209565

9

Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation.

Bergo MO, Ambroziak P, Gregory C, George A, Otto JC, Kim E, Nagase H, Casey PJ, Balmain A, Young SG. Bergo MO, et al. Among authors: otto jc. Mol Cell Biol. 2002 Jan;22(1):171-81. doi: 10.1128/MCB.22.1.171-181.2002. Mol Cell Biol. 2002. PMID: 11739732 Free PMC article.

10

Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.

Fridy PC, Otto JC, Dollins DE, York JD. Fridy PC, et al. Among authors: otto jc. J Biol Chem. 2007 Oct 19;282(42):30754-62. doi: 10.1074/jbc.M704656200. Epub 2007 Aug 9. J Biol Chem. 2007. PMID: 17690096 Free article.

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