The role of mismatched nucleotides in activating the hMSH2-hMSH6 molecular switch.
Gradia S, Acharya S, Fishel R.
Gradia S, et al. Among authors: fishel r.
J Biol Chem. 2000 Feb 11;275(6):3922-30. doi: 10.1074/jbc.275.6.3922.
J Biol Chem. 2000.
PMID: 10660545
Free article.
These studies suggested that mismatch repair could be propagated by a signaling event transduced via diffusion of ATP-bound hMSH2-hMSH6 molecular switches to the DNA repair machinery. The Molecular Switch model (Fishel, R. (1998) Genes Dev. 12, 2096-2101) is conside …
These studies suggested that mismatch repair could be propagated by a signaling event transduced via diffusion of ATP-bound hMSH2-hMSH6 mole …