Dreier B - Search Results

1

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences.

Segal DJ, Dreier B, Beerli RR, Barbas CF 3rd. Segal DJ, et al. Among authors: dreier b. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2758-63. doi: 10.1073/pnas.96.6.2758. Proc Natl Acad Sci U S A. 1999. PMID: 10077584 Free PMC article.

2

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks.

Beerli RR, Segal DJ, Dreier B, Barbas CF 3rd. Beerli RR, et al. Among authors: dreier b. Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14628-33. doi: 10.1073/pnas.95.25.14628. Proc Natl Acad Sci U S A. 1998. PMID: 9843940 Free PMC article.

3

Positive and negative regulation of endogenous genes by designed transcription factors.

Beerli RR, Dreier B, Barbas CF 3rd. Beerli RR, et al. Among authors: dreier b. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1495-500. doi: 10.1073/pnas.040552697. Proc Natl Acad Sci U S A. 2000. PMID: 10660690 Free PMC article.

4

Chemically regulated zinc finger transcription factors.

Beerli RR, Schopfer U, Dreier B, Barbas CF 3rd. Beerli RR, et al. Among authors: dreier b. J Biol Chem. 2000 Oct 20;275(42):32617-27. doi: 10.1074/jbc.M005108200. J Biol Chem. 2000. PMID: 10924515 Free article.

5

Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains.

Dreier B, Segal DJ, Barbas CF 3rd. Dreier B, et al. J Mol Biol. 2000 Nov 3;303(4):489-502. doi: 10.1006/jmbi.2000.4133. J Mol Biol. 2000. PMID: 11054286

6

Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors.

Dreier B, Beerli RR, Segal DJ, Flippin JD, Barbas CF 3rd. Dreier B, et al. J Biol Chem. 2001 Aug 3;276(31):29466-78. doi: 10.1074/jbc.M102604200. Epub 2001 May 4. J Biol Chem. 2001. PMID: 11340073 Free article.

In previous studies we have developed Cys(2)-His(2) zinc finger domains that specifically recognized each of the 16 5'-GNN-3' DNA target sequences and could be used to assemble six-finger proteins that bind 18-base pair DNA sequences (Beerli, R. R., Dreier, B., and …

In previous studies we have developed Cys(2)-His(2) zinc finger domains that specifically recognized each of the 16 5'-GNN-3' DNA target seq …

7

Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins.

Segal DJ, Beerli RR, Blancafort P, Dreier B, Effertz K, Huber A, Koksch B, Lund CV, Magnenat L, Valente D, Barbas CF 3rd. Segal DJ, et al. Among authors: dreier b. Biochemistry. 2003 Feb 25;42(7):2137-48. doi: 10.1021/bi026806o. Biochemistry. 2003. PMID: 12590603

8

Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors.

Dreier B, Fuller RP, Segal DJ, Lund CV, Blancafort P, Huber A, Koksch B, Barbas CF 3rd. Dreier B, et al. J Biol Chem. 2005 Oct 21;280(42):35588-97. doi: 10.1074/jbc.M506654200. Epub 2005 Aug 17. J Biol Chem. 2005. PMID: 16107335 Free article.

9

A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end.

Pecqueur L, Duellberg C, Dreier B, Jiang Q, Wang C, Plückthun A, Surrey T, Gigant B, Knossow M. Pecqueur L, et al. Among authors: dreier b. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12011-6. doi: 10.1073/pnas.1204129109. Epub 2012 Jul 9. Proc Natl Acad Sci U S A. 2012. PMID: 22778434 Free PMC article.

10

Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters.

Dreier B, Honegger A, Hess C, Nagy-Davidescu G, Mittl PR, Grütter MG, Belousova N, Mikheeva G, Krasnykh V, Plückthun A. Dreier B, et al. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):E869-77. doi: 10.1073/pnas.1213653110. Epub 2013 Feb 19. Proc Natl Acad Sci U S A. 2013. PMID: 23431166 Free PMC article.

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