Hiltunen JK - Search Results

1

Mutagenic and enzymological studies of the hydratase and isomerase activities of 2-enoyl-CoA hydratase-1.

Kiema TR, Engel CK, Schmitz W, Filppula SA, Wierenga RK, Hiltunen JK. Kiema TR, et al. Among authors: hiltunen jk. Biochemistry. 1999 Mar 9;38(10):2991-9. doi: 10.1021/bi981646v. Biochemistry. 1999. PMID: 10074351

2

The isomerase and hydratase reaction mechanism of the crotonase active site of the multifunctional enzyme (type-1), as deduced from structures of complexes with 3S-hydroxy-acyl-CoA.

Kasaragod P, Schmitz W, Hiltunen JK, Wierenga RK. Kasaragod P, et al. Among authors: hiltunen jk. FEBS J. 2013 Jul;280(13):3160-75. doi: 10.1111/febs.12150. Epub 2013 Feb 15. FEBS J. 2013. PMID: 23351063 Free article.

3

Crystallization and characterization of the dehydrogenase domain from rat peroxisomal multifunctional enzyme type 1.

Taskinen JP, Kiema TR, Koivuranta KT, Wierenga RK, Hiltunen JK. Taskinen JP, et al. Among authors: hiltunen jk. Acta Crystallogr D Biol Crystallogr. 2002 Apr;58(Pt 4):690-3. doi: 10.1107/s0907444902001890. Epub 2002 Mar 22. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 11914498

4

Organization of the multifunctional enzyme type 1: interaction between N- and C-terminal domains is required for the hydratase-1/isomerase activity.

Kiema TR, Taskinen JP, Pirilä PL, Koivuranta KT, Wierenga RK, Hiltunen JK. Kiema TR, et al. Among authors: hiltunen jk. Biochem J. 2002 Oct 15;367(Pt 2):433-41. doi: 10.1042/BJ20020292. Biochem J. 2002. PMID: 12106015 Free PMC article.

5

Structural studies on delta(3)-delta(2)-enoyl-CoA isomerase: the variable mode of assembly of the trimeric disks of the crotonase superfamily.

Mursula AM, Hiltunen JK, Wierenga RK. Mursula AM, et al. Among authors: hiltunen jk. FEBS Lett. 2004 Jan 16;557(1-3):81-7. doi: 10.1016/s0014-5793(03)01450-9. FEBS Lett. 2004. PMID: 14741345 Free article.

6

The 1.3 A crystal structure of human mitochondrial Delta3-Delta2-enoyl-CoA isomerase shows a novel mode of binding for the fatty acyl group.

Partanen ST, Novikov DK, Popov AN, Mursula AM, Hiltunen JK, Wierenga RK. Partanen ST, et al. Among authors: hiltunen jk. J Mol Biol. 2004 Sep 24;342(4):1197-208. doi: 10.1016/j.jmb.2004.07.039. J Mol Biol. 2004. PMID: 15351645

7

Crystallographic binding studies of rat peroxisomal multifunctional enzyme type 1 with 3-ketodecanoyl-CoA: capturing active and inactive states of its hydratase and dehydrogenase catalytic sites.

Sridhar S, Schmitz W, Hiltunen JK, Venkatesan R, Bergmann U, Kiema TR, Wierenga RK. Sridhar S, et al. Among authors: hiltunen jk. Acta Crystallogr D Struct Biol. 2020 Dec 1;76(Pt 12):1256-1269. doi: 10.1107/S2059798320013819. Epub 2020 Nov 24. Acta Crystallogr D Struct Biol. 2020. PMID: 33263331

8

Delta3,5-delta2,4-dienoyl-CoA isomerase from rat liver. Molecular characterization.

Filppula SA, Yagi AI, Kilpeläinen SH, Novikov D, FitzPatrick DR, Vihinen M, Valle D, Hiltunen JK. Filppula SA, et al. Among authors: hiltunen jk. J Biol Chem. 1998 Jan 2;273(1):349-55. doi: 10.1074/jbc.273.1.349. J Biol Chem. 1998. PMID: 9417087 Free article.

9

Crystallization and X-ray diffraction analysis of peroxisomal Delta3-Delta2-enoyl-CoA isomerase from Saccharomyces cerevisiae.

Mursula AM, van Aalten DM, Modis Y, Hiltunen JK, Wierenga RK. Mursula AM, et al. Among authors: hiltunen jk. Acta Crystallogr D Biol Crystallogr. 2000 Aug;56(Pt 8):1020-3. doi: 10.1107/s0907444900006533. Acta Crystallogr D Biol Crystallogr. 2000. PMID: 10944342

10

The crystal structure of delta(3)-delta(2)-enoyl-CoA isomerase.

Mursula AM, van Aalten DM, Hiltunen JK, Wierenga RK. Mursula AM, et al. Among authors: hiltunen jk. J Mol Biol. 2001 Jun 15;309(4):845-53. doi: 10.1006/jmbi.2001.4671. J Mol Biol. 2001. PMID: 11399063

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