Noordhuis P - Search Results

1

Role of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in methotrexate accumulation and polyglutamylation in childhood leukemia.

Rots MG, Pieters R, Peters GJ, Noordhuis P, van Zantwijk CH, Kaspers GJ, Hählen K, Creutzig U, Veerman AJ, Jansen G. Rots MG, et al. Among authors: noordhuis p. Blood. 1999 Mar 1;93(5):1677-83. Blood. 1999. PMID: 10029597 Free article. Clinical Trial.

2

Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia.

Stam RW, den Boer ML, Meijerink JP, Ebus ME, Peters GJ, Noordhuis P, Janka-Schaub GE, Armstrong SA, Korsmeyer SJ, Pieters R. Stam RW, et al. Among authors: noordhuis p. Blood. 2003 Feb 15;101(4):1270-6. doi: 10.1182/blood-2002-05-1600. Epub 2002 Oct 24. Blood. 2003. PMID: 12406912 Free article.

3

Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.

Rots MG, Pieters R, Kaspers GJ, van Zantwijk CH, Noordhuis P, Mauritz R, Veerman AJ, Jansen G, Peters GJ. Rots MG, et al. Among authors: noordhuis p. Blood. 1999 Feb 1;93(3):1067-74. Blood. 1999. PMID: 9920857 Free article.

4

Circumvention of methotrexate resistance in childhood leukemia subtypes by rationally designed antifolates.

Rots MG, Pieters R, Peters GJ, van Zantwijk CH, Mauritz R, Noordhuis P, Willey JC, Hählen K, Creutzig U, Janka-Schaub G, Kaspers GJ, Veerman AJ, Jansen G. Rots MG, et al. Among authors: noordhuis p. Blood. 1999 Nov 1;94(9):3121-8. Blood. 1999. PMID: 10556198 Free article.

5

Methotrexate resistance in relapsed childhood acute lymphoblastic leukaemia.

Rots MG, Pieters R, Peters GJ, Noordhuis P, Van Zantwijk CH, Henze G, Janka-Schaub GE, Veerman AJ, Jansen G. Rots MG, et al. Among authors: noordhuis p. Br J Haematol. 2000 Jun;109(3):629-34. doi: 10.1046/j.1365-2141.2000.02071.x. Br J Haematol. 2000. PMID: 10886214 Free article.

6

mRNA expression levels of methotrexate resistance-related proteins in childhood leukemia as determined by a standardized competitive template-based RT-PCR method.

Rots MG, Willey JC, Jansen G, Van Zantwijk CH, Noordhuis P, DeMuth JP, Kuiper E, Veerman AJ, Pieters R, Peters GJ. Rots MG, et al. Among authors: noordhuis p. Leukemia. 2000 Dec;14(12):2166-75. doi: 10.1038/sj.leu.2401943. Leukemia. 2000. PMID: 11187907

7

A possible role for methotrexate in the treatment of childhood acute myeloid leukaemia, in particular for acute monocytic leukaemia.

Rots MG, Pieters R, Jansen G, Kaspers GJ, Van Zantwijk CH, Noordhuis P, Voorn DA, Van Wering ER, Creutzig U, Veerman AJ, Peters GJ. Rots MG, et al. Among authors: noordhuis p. Eur J Cancer. 2001 Mar;37(4):492-8. doi: 10.1016/s0959-8049(00)00433-0. Eur J Cancer. 2001. PMID: 11267859

8

Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.

Mauritz R, Peters GJ, Priest DG, Assaraf YG, Drori S, Kathmann I, Noordhuis P, Bunni MA, Rosowsky A, Schornagel JH, Pinedo HM, Jansen G. Mauritz R, et al. Among authors: noordhuis p. Biochem Pharmacol. 2002 Jan 15;63(2):105-15. doi: 10.1016/s0006-2952(01)00824-3. Biochem Pharmacol. 2002. PMID: 11841783

9

Importance of pharmacodynamics in the in vitro antiproliferative activity of the antifolates methotrexate and 10-ethyl-10-deazaaminopterin against human head and neck squamous cell carcinoma.

Braakhuis BJ, Jansen G, Noordhuis P, Kegel A, Peters GJ. Braakhuis BJ, et al. Among authors: noordhuis p. Biochem Pharmacol. 1993 Dec 14;46(12):2155-61. doi: 10.1016/0006-2952(93)90604-u. Biochem Pharmacol. 1993. PMID: 7506025

10

Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.

van Triest B, Pinedo HM, van Hensbergen Y, Smid K, Telleman F, Schoenmakers PS, van der Wilt CL, van Laar JA, Noordhuis P, Jansen G, Peters GJ. van Triest B, et al. Among authors: noordhuis p. Clin Cancer Res. 1999 Mar;5(3):643-54. Clin Cancer Res. 1999. PMID: 10100718

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