Abstract
We report an intracranial leiomyosarcoma in the pontine cistern of a 34-year-old woman infected with the human immunodeficiency virus (HIV). The clinical, radiological and pathological data are reviewed. The tumor was Epstein-Barr virus (EBV) positive by in situ hybridization. This case emphasizes that smooth muscle neoplasms arising in the setting of immunocompromise can occur intracranially, and corroborates a hypothesis that EBV coinfection may have a role in development of these tumors.
MeSH terms
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Acquired Immunodeficiency Syndrome / complications*
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Adult
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Brain / diagnostic imaging
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Brain / pathology
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Brain Neoplasms / complications*
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Brain Neoplasms / diagnosis
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Brain Neoplasms / pathology
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Brain Neoplasms / virology
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Epstein-Barr Virus Infections / complications
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Female
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Herpesvirus 4, Human / isolation & purification
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Humans
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Leiomyosarcoma / complications*
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Leiomyosarcoma / diagnosis
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Leiomyosarcoma / pathology
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Leiomyosarcoma / virology
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Magnetic Resonance Imaging
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Tomography, X-Ray Computed