A new single-photon emission computed tomography imaging agent for serotonin transporters: [123I]IDAM, 5-iodo-2-((2-((dimethylamino)methyl)phenyl)thio)benzyl alcohol

J Med Chem. 1999 Feb 11;42(3):333-5. doi: 10.1021/jm9806751.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Benzyl Alcohols / chemical synthesis
  • Benzyl Alcohols / chemistry
  • Benzyl Alcohols / pharmacokinetics*
  • Brain / metabolism
  • Carrier Proteins / analysis*
  • Contrast Media / chemical synthesis
  • Contrast Media / chemistry
  • Contrast Media / pharmacokinetics*
  • Iodine Radioisotopes
  • LLC-PK1 Cells
  • Magnetic Resonance Imaging
  • Membrane Glycoproteins / analysis*
  • Membrane Transport Proteins*
  • Nerve Tissue Proteins*
  • Papio
  • Rats
  • Serotonin Plasma Membrane Transport Proteins
  • Sulfides / chemical synthesis
  • Sulfides / chemistry
  • Sulfides / pharmacokinetics*
  • Swine
  • Tissue Distribution
  • Tomography, Emission-Computed, Single-Photon

Substances

  • 5-iodo-2-((2-((methylamino)methyl)phenyl)thio)benzyl alcohol
  • Benzyl Alcohols
  • Carrier Proteins
  • Contrast Media
  • Iodine Radioisotopes
  • Membrane Glycoproteins
  • Membrane Transport Proteins
  • Nerve Tissue Proteins
  • Serotonin Plasma Membrane Transport Proteins
  • Slc6a4 protein, rat
  • Sulfides