The adequacy of therapeutic program for hypertensive disease in the patients with ischemic brain disease was analyzed in the study related to the administration of the drugs divided by the groups of antihypertensive drugs. The results had demonstrated that in over 50% patients the therapy had to be changed by introducing at least one hypertensive drug from the other group. In many cases were observed inadequate doses of antihypertensive drugs and the prescription of antihypertensive drug in minimal dose, although therapeutic response was not adequate. In significant number of cases (over 80%), the patients were irregularly taking the prescribed therapy, and only 18% had the regular controls. The results of this investigation indicated that on one side did not exist the adequate therapeutic program for hypertension control and on the other the significant number of patients irregularly used the proposed therapy and did not control the disease regularly.