Mitomycin C trabeculectomy in eyes with cicatricial conjunctiva

Am J Ophthalmol. 1998 Dec;126(6):823-4. doi: 10.1016/s0002-9394(98)00185-8.

Abstract

Purpose: To demonstrate favorable outcome of mitomycin C-augmented trabeculectomy in eyes with broad cicatricial conjunctiva created by previous surgeries.

Methods: Forty-six eyes (40 patients) with extensive conjunctival scarring that had undergone mitomycin C trabeculectomy were reviewed retrospectively.

Results: After a mean follow-up +/- SD of 13.7 +/- 7.8 months (range, 6 to 36 months), intraocular pressure was well controlled, below or equal to 16 mm Hg and 21 mm Hg, respectively, in 33 (72%) and 44 (96%) of the 46 eyes. In all eyes, a functional filtering bleb was present during the follow-up periods.

Conclusion: Mitomycin C trabeculectomy after dissection of conjunctival scar tissue may be useful for treating refractory glaucoma.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Chemotherapy, Adjuvant
  • Cicatrix / complications
  • Cicatrix / surgery*
  • Conjunctival Diseases / complications
  • Conjunctival Diseases / surgery*
  • Follow-Up Studies
  • Glaucoma / drug therapy*
  • Glaucoma / surgery*
  • Humans
  • Intraocular Pressure
  • Middle Aged
  • Mitomycin / therapeutic use*
  • Trabeculectomy*

Substances

  • Mitomycin