A highly polymorphic CA repeat marker at the human interleukin 6 receptor (IL6R) locus

K Tsukamoto; N Ohta; Y Shirai; M Emi

doi:10.1007/s100380050095

A highly polymorphic CA repeat marker at the human interleukin 6 receptor (IL6R) locus

J Hum Genet. 1998;43(4):289-90. doi: 10.1007/s100380050095.

Authors

K Tsukamoto¹, N Ohta, Y Shirai, M Emi

Affiliation

¹ Department of Molecular Biology, Nippon Medical School, Kawasaki, Japan.

PMID: 9852689
DOI: 10.1007/s100380050095

Abstract

A polymorphic dinucleotide (CA) sequence was isolated from a genomic clone containing the human interleukin 6 receptor (IL6R) gene. High heterozygosity (0.81) makes this polymorphism a useful marker in the genetic study of disorders affecting the inflammation process and bone resorption.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Bone Resorption / genetics
Chromosomes, Human, Pair 1*
Dinucleotide Repeats*
Gene Frequency
Genetic Markers
Humans
Polymorphism, Genetic
Receptors, Interleukin-6 / genetics*

Substances

Genetic Markers
Receptors, Interleukin-6