Normal intrasylvian anatomical asymmetry in children with developmental language disorder

Neuropsychologia. 1998 Sep;36(9):849-55. doi: 10.1016/s0028-3932(98)00033-5.

Abstract

Symmetry of posterior intrasylvian cortices (e.g., planum temporale, planum parietale) has been suggested to represent a risk factor for developmental disorders of language and reading. Using high-resolution magnetic resonance morphometry, we studied 21 right-handed children with developmental language disorder of the phonologic-syntactic type, and found normal left-right asymmetry of the planum temporale and planum parietale when compared with 21 matched controls. The planum temporale was bilaterally smaller in the affected children, a finding accounted for by their approximately 7% smaller forebrain size. Our data do not support a role of gross visible unilateral or bilateral abnormalities of posterior intrasylvian ontogenesis in this disorder.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analysis of Variance
  • Anthropometry
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Female
  • Functional Laterality
  • Humans
  • Language Development Disorders / classification
  • Language Development Disorders / pathology*
  • Magnetic Resonance Imaging
  • Male
  • Parietal Lobe / pathology*
  • Prosencephalon / pathology
  • Regression Analysis
  • Temporal Lobe / pathology*