The expression patterns of endothelin-A receptor and endothelin 1 in the avian embryo

Mech Dev. 1998 Jul;75(1-2):145-9. doi: 10.1016/s0925-4773(98)00079-3.

Abstract

We investigated the expression pattern of the endothelin-A receptor and endothelin 1 genes, the mutations of which affect the development of the mesectodermal derivatives of the neural crest. We show here that endothelin 1 is expressed by the environment of the cephalic neural crest cells invading branchial arches. Later on, while the neural crest-derived tissues of the head continue to express endothelin-A receptor, endothelin 1 is no longer expressed in their environment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chick Embryo
  • Embryo, Nonmammalian / metabolism*
  • Endothelin-1 / genetics*
  • Gene Expression Regulation, Developmental
  • In Situ Hybridization
  • Receptor, Endothelin A
  • Receptors, Endothelin / genetics*

Substances

  • Endothelin-1
  • Receptor, Endothelin A
  • Receptors, Endothelin