Primary pulmonary plasmacytoma with lobar consolidation: an unusual presentation

J Formos Med Assoc. 1998 Jul;97(7):507-10.

Abstract

Extramedullary plasmacytoma is a rare form of plasma cell tumor that frequently involves the upper respiratory tract. Primary pulmonary plasmacytoma is even more rare. The usual presentation of primary pulmonary plasmacytoma is a solitary pulmonary nodule. We describe the case of a 58-year-old woman who presented with the chief complaints of progressive dyspnea on exertion, cough, and subsequently, hemoptysis. The main finding on chest imaging studies, including plain radiography, sonography, computed tomography, and magnetic resonance imaging, was consolidation of the right middle lobe. Percutaneous transthoracic lung biopsy of the right middle lobe demonstrated sheets of atypical plasma cells. Immunohistochemical study showed IgA lambda monoclonality. A bone marrow study and whole body bone scan showed normal findings. To the best of our knowledge, this is the first reported case of primary pulmonary plasmacytoma presenting with lobar consolidation of the lung but without a well-defined tumor mass.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Needle
  • Female
  • Humans
  • Lung / pathology
  • Lung Neoplasms / complications
  • Lung Neoplasms / pathology*
  • Lung Neoplasms / therapy
  • Middle Aged
  • Plasmacytoma / complications
  • Plasmacytoma / pathology*
  • Plasmacytoma / therapy
  • Pleural Effusion / etiology