Favorable outcome of giant cell glioblastoma in a child. Report of an 11-year survival period

Childs Nerv Syst. 1998 Jun;14(6):288-91. doi: 10.1007/s003810050228.

Abstract

Giant cell glioblastomas are defined as glioblastomas with a marked predominance of bizarre, multinucleated giant cells. They represent about 5% of all glioblastomas and can occur at any site of the central nervous system, but the temporal and frontal lobes are the sites of predilection. Overall, giant cell glioblastomas show a prolonged survival period compared with common glioblastoma multiforme, and survival periods of 7 and 9 years have been reported in adults. Here we report on a child aged 11 years at diagnosis, who has so far survived for 11 years since operation and adjunctive radio- and chemotherapy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Brain Neoplasms / drug therapy
  • Brain Neoplasms / pathology
  • Brain Neoplasms / radiotherapy
  • Brain Neoplasms / surgery*
  • Chemotherapy, Adjuvant
  • Child
  • Disease-Free Survival
  • Female
  • Follow-Up Studies
  • Glioblastoma / drug therapy
  • Glioblastoma / pathology
  • Glioblastoma / radiotherapy
  • Glioblastoma / surgery*
  • Humans
  • Radiotherapy, Adjuvant
  • Temporal Lobe / pathology
  • Temporal Lobe / surgery*