Endovascular stent graft repair for aneurysms on the descending thoracic aorta

Ann Thorac Surg. 1998 Jul;66(1):19-24; discussion 24-5. doi: 10.1016/s0003-4975(98)00390-7.

Abstract

Background: The traditional treatment of aneurysms of the descending thoracic aorta includes posterolateral thoracotomy and aortic replacement with a prosthetic graft. In this study, we report our experiences and results in endovascular stent graft placement as an alternative to surgical repair.

Methods: Between January 1989 and July 1997, a total of 68 patients (24 women) underwent replacement of the thoracic aorta. Mean age at operation was 51 years. Fifty-eight patients underwent conventional surgical treatment. All of these patients were suitable candidates for endovascular stenting; however, no stent graft material was available at the time of operation. Ten patients (1 chronic dissection, 9 atherosclerotic aneurysm) received in the past 8 months the first commercially manufactured endovascular stent graft. The mean diameter of the aneurysms in this group was 7 cm (range, 6 to 8 cm). Two stent patients were operated on using only spinal cord analgesia. All stent grafts were custom designed for each of the 10 patients.

Results: The 30-day mortality in the conventional group was 31% versus 10% in the stent group. Mean length of intervention was 320 minutes in the conventional group versus 150 minutes in the endovascular group. Spinal cord injury occurred in 5 patients (12%) in the surgical group, whereas none of the stented patients developed any neurologic sequelae. Mean intensive care unit stay was 13 days, followed by a mean of 10 days on a ward in the first group compared to 4 days in the intensive care unit and 6 days on the ward in the stent group. One stent was required in 2 patients, two stents were required in 3 patients, and four stents were deployed in 5 patients of our series. Five patients required transposition of the left subclavian artery to achieve a sufficient neck for the proximal placement of the stent. There was complete thrombosis of the thoracic aortic aneurysm surrounding the stent graft in 8 patients (80%). Two patients required restenting as a result of leakage (20%). Stent graft placing was performed through the femoral artery in 8 patients, whereas access was only achieved through the abdominal aorta in 2 patients.

Conclusions: These preliminary results demonstrate that endovascular stent graft replacement might be a promising, cheaper, and safe alternative method in selected patients with descending thoracic aneurysms.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Anesthesia, General
  • Anesthesia, Spinal
  • Aorta, Abdominal
  • Aortic Aneurysm, Thoracic / pathology
  • Aortic Aneurysm, Thoracic / surgery
  • Aortic Aneurysm, Thoracic / therapy*
  • Aortic Dissection / therapy
  • Arteriosclerosis / therapy
  • Blood Vessel Prosthesis Implantation / adverse effects
  • Catheterization, Peripheral
  • Chronic Disease
  • Critical Care
  • Equipment Design
  • Female
  • Femoral Artery
  • Humans
  • Length of Stay
  • Male
  • Middle Aged
  • Retreatment
  • Spinal Cord Diseases / etiology
  • Stents* / adverse effects
  • Subclavian Artery / surgery
  • Survival Rate
  • Thrombosis / pathology
  • Time Factors