A novel orally active endothelin-A receptor antagonist, ZD1611, prevents chronic hypoxia-induced pulmonary hypertension in the rat

Chest. 1998 Jul;114(1 Suppl):91S. doi: 10.1378/chest.114.1_supplement.91s.

Authors

R A Bialecki¹, C Stinson-Fisher, W Murdoch, D Bertelsen, M Desiato, W Rumsey

Affiliation

¹ BioMedical Research Station, Zeneca, Inc, Wilmington, Del, USA.

PMID: 9676649
DOI: 10.1378/chest.114.1_supplement.91s

No abstract available

MeSH terms

Animals
Chronic Disease
Endothelin Receptor Antagonists*
Hypertension, Pulmonary / etiology
Hypertension, Pulmonary / prevention & control*
Hypoxia / complications*
In Vitro Techniques
Male
Rats
Rats, Sprague-Dawley
Receptor, Endothelin A

Substances

Endothelin Receptor Antagonists
Receptor, Endothelin A