A case of accelerated development of proliferative diabetic retinopathy in a woman with type 2 diabetes mellitus after pregnancy

Ann Acad Med Singap. 1998 Mar;27(2):265-8.

Abstract

Whilst it is recognised that diabetic retinopathy is a consequence of prolonged elevation of blood glucose levels, recent studies suggest rapid normalisation of blood sugar as a causal factor in accelerating its development. In this case report, a non-insulin dependent diabetic with poor blood glucose control but no retinopathy in early pregnancy had normalisation of glucose control by the third trimester. However, glucose control deteriorated rapidly postnatally, and she had a sudden blurring of vision three months after delivery of her baby, at which time severe proliferative diabetic retinopathy was diagnosed. The reason for the unusually rapid development of proliferative retinopathy was uncertain, but appeared to have a temporal association with the deterioration of her glycaemic control postnatal after a period of strict diabetes control in the perinatal period.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Blood Glucose / analysis
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / physiopathology*
  • Diabetes Mellitus, Type 2 / prevention & control
  • Diabetic Retinopathy / diagnosis*
  • Female
  • Follow-Up Studies
  • Glycated Hemoglobin / analysis
  • Humans
  • Hyperglycemia / prevention & control
  • Neovascularization, Pathologic / diagnosis
  • Pregnancy
  • Pregnancy in Diabetics / blood
  • Pregnancy in Diabetics / physiopathology*
  • Pregnancy in Diabetics / prevention & control
  • Vision Disorders / diagnosis

Substances

  • Blood Glucose
  • Glycated Hemoglobin A