Abstract
The paper presents data available in the literature and the author's own experimental findings as to the construction of chimeric hepatitis B core antigen (HBcAg) particles. The problems associated with the design of hybrid HBcAg particles and the ways of solving arising problems are considered. Data from studies of the antigen and immunogenic properties of hybrid HBcAg particles.
MeSH terms
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Animals
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Antigen Presentation / immunology*
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Epitopes, T-Lymphocyte / chemistry
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Epitopes, T-Lymphocyte / immunology*
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Hepatitis B Antibodies / immunology
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Hepatitis B Core Antigens / immunology*
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Hepatitis B virus / immunology*
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Humans
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Recombinant Fusion Proteins / chemistry
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Recombinant Fusion Proteins / immunology*
Substances
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Epitopes, T-Lymphocyte
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Hepatitis B Antibodies
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Hepatitis B Core Antigens
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Recombinant Fusion Proteins