Fatal suppurative mesenteric thrombophlebitis caused by an Enterococcus faecalis highly resistant to aminoglycosides: case report

J Chemother. 1998 Apr;10(2):128-31. doi: 10.1179/joc.1998.10.2.128.

Abstract

A 56-year old man with non-Hodgkin's lymphoma and biliary tract endoprosthesis, developed chronic bacteremia caused by Enterococcus faecalis with high-level resistance to gentamicin and streptomycin. The sources of bacteremia were a device-associated biliary tract infection, a suppurative thrombophlebitis of the confluence of the superior mesenteric vein with the splenic vein as well as multiple liver and pancreatic abscesses. Despite antibiotic therapy and multiple drainages of abscesses, the patient died due to overwhelming infection.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use*
  • Bacteremia / complications
  • Bacteremia / drug therapy
  • Drug Resistance, Microbial
  • Enterococcus faecalis / drug effects*
  • Fatal Outcome
  • Gentamicins / administration & dosage
  • Gentamicins / therapeutic use*
  • Gram-Positive Bacterial Infections / drug therapy*
  • Gram-Positive Bacterial Infections / microbiology
  • Humans
  • Lymphoma, Non-Hodgkin / complications
  • Male
  • Mesenteric Veins / microbiology
  • Mesenteric Veins / pathology*
  • Microbial Sensitivity Tests
  • Middle Aged
  • Splenic Vein / microbiology
  • Splenic Vein / pathology
  • Streptomycin / administration & dosage
  • Streptomycin / therapeutic use*
  • Suppuration / microbiology
  • Thrombosis / drug therapy*
  • Thrombosis / microbiology*
  • Treatment Failure

Substances

  • Anti-Bacterial Agents
  • Gentamicins
  • Streptomycin