Transient regression of an intracranial germ cell tumour after intravenous steroid administration: a case report

J Neurol Neurosurg Psychiatry. 1998 May;64(5):670-2. doi: 10.1136/jnnp.64.5.670.

Abstract

Magnetic resonance imaging showed transient regression of the lesion after intravenous steroid administration in a patient with intracranial multifocal germ cell tumour. Prominent lymphocyte infiltration of the tumour was seen at histological examination and presumably accounts for the regression. Germ cell tumour must be included in the differential diagnosis of intracranial mass lesions sensitive to steroids.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antineoplastic Agents, Hormonal / administration & dosage*
  • Biopsy
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / drug therapy*
  • Brain Neoplasms / pathology
  • Carcinoma, Embryonal / diagnosis
  • Carcinoma, Embryonal / drug therapy*
  • Carcinoma, Embryonal / pathology
  • Caudate Nucleus / pathology
  • Female
  • Follow-Up Studies
  • Humans
  • Magnetic Resonance Imaging
  • Neoplasms, Multiple Primary / diagnosis
  • Neoplasms, Multiple Primary / drug therapy*
  • Neoplasms, Multiple Primary / pathology
  • Paraneoplastic Endocrine Syndromes / diagnosis
  • Paraneoplastic Endocrine Syndromes / drug therapy
  • Paraneoplastic Endocrine Syndromes / pathology
  • Pituitary Gland / pathology
  • Pituitary Neoplasms / diagnosis
  • Pituitary Neoplasms / drug therapy*
  • Pituitary Neoplasms / pathology
  • Prednisone / administration & dosage*
  • Stereotaxic Techniques
  • Treatment Outcome

Substances

  • Antineoplastic Agents, Hormonal
  • Prednisone