Transcriptional regulation of the human proenkephalin gene by conformational switching: implications for decoy design

Antisense Nucleic Acid Drug Dev. 1998 Apr;8(2):159-65. doi: 10.1089/oli.1.1998.8.159.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Base Sequence
  • Consensus Sequence
  • Cyclic AMP Response Element-Binding Protein / metabolism
  • DNA, Recombinant / genetics
  • Drug Design*
  • Enhancer Elements, Genetic / drug effects
  • Enhancer Elements, Genetic / genetics
  • Enkephalins / biosynthesis
  • Enkephalins / genetics*
  • Genes*
  • Humans
  • Molecular Sequence Data
  • Molecular Structure
  • Nucleic Acid Conformation / drug effects*
  • Oligonucleotides, Antisense / chemistry
  • Oligonucleotides, Antisense / pharmacology*
  • Plasmids / genetics
  • Protein Binding
  • Protein Precursors / biosynthesis
  • Protein Precursors / genetics*
  • Structure-Activity Relationship
  • Thionucleotides / chemistry
  • Thionucleotides / pharmacology
  • Transcription, Genetic / drug effects*
  • Transcriptional Activation / drug effects

Substances

  • Cyclic AMP Response Element-Binding Protein
  • DNA, Recombinant
  • Enkephalins
  • Oligonucleotides, Antisense
  • Protein Precursors
  • Thionucleotides
  • proenkephalin