[How can we measure a diameter of each entrance of a ion channel recording only channel conductance?]

Biofizika. 1998 Mar-Apr;43(2):299-303.
[Article in Russian]

Abstract

The channel formed by colicin Ia in planar lipid bilayer was used to develop a method determining a diameter of each channel entrance. The method is based on measuring of a channel filling with nonelectrolytes through cis- and trans-entrance separately. To do this, one need to establish the two things only: the conductance of an ion channel and the conductivity of used solutions. Using the method to predict the internal geometry of a channel lumen is discussed.

Publication types

  • English Abstract

MeSH terms

  • Colicins / chemistry*
  • Electrophysiology / methods*
  • Ion Channel Gating
  • Ion Channels / chemistry*
  • Ion Channels / physiology
  • Lipid Bilayers / chemistry*

Substances

  • Colicins
  • Ion Channels
  • Lipid Bilayers