The effectiveness of modified ingram therapy compared with severity of psoriasis

J Dermatol. 1998 Feb;25(2):112-7. doi: 10.1111/j.1346-8138.1998.tb02360.x.

Abstract

To treat cases of psoriasis, various modifications of the original Ingram method were tested for increased effectiveness and minimized side reactions. Our modified method consists of 0.1-0.5% anthralin ointment application and selective UVB phototherapy with adjunctive warm water bath and the application of emollients. The object of this study was to evaluate the effectiveness and duration of remission in response to our modified Ingram method and compare the data with the severity of psoriasis. The clearing rate was higher and the failure rate was lower in the moderate group. The number of occasions on which therapy was used and the duration of this therapy were greater in the severe group, but there were no significant differences except for the number of occasions of therapy to the trunk. Fifty-eight percent of the moderate group did not relapse in more than one year, but 63% of the severe group relapsed within six months. The results of this study showed that the modified Ingram regimen is an effective therapeutic modality in psoriasis, especially in the moderate group.

Publication types

  • Clinical Trial
  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Topical
  • Adult
  • Aged
  • Anthralin / therapeutic use*
  • Anti-Inflammatory Agents / therapeutic use*
  • Combined Modality Therapy
  • Female
  • Humans
  • Hydrotherapy
  • Male
  • Middle Aged
  • Petrolatum / therapeutic use
  • Prognosis
  • Psoriasis / radiotherapy
  • Psoriasis / therapy*
  • Recurrence
  • Severity of Illness Index
  • Treatment Outcome
  • Ultraviolet Therapy

Substances

  • Anti-Inflammatory Agents
  • Petrolatum
  • Anthralin