Theoretical basis for interest in acetylprocainamide and clinical experiences with this new antiarrhythmic agent

Drug Metab Rev. 1979;10(2):239-46. doi: 10.3109/03602537908997471.

Abstract

In conclusion, it was the differential responses of slow and rapid acetylators to procainamide therapy that gave the initial clues that acetylprocainamide might be a safer drug than procainamide. So far, the experience with acetylprocainamide has been encouraging.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acecainide / adverse effects
  • Acecainide / pharmacology*
  • Acecainide / therapeutic use
  • Acetylation
  • Animals
  • Arrhythmias, Cardiac / drug therapy
  • Isomerism
  • Kinetics
  • Procainamide / analogs & derivatives*
  • Procainamide / metabolism

Substances

  • Acecainide
  • Procainamide