Purification and characterization of a novel glutathione transferase from Ochrobactrum anthropi

FEMS Microbiol Lett. 1998 Mar 1;160(1):81-6. doi: 10.1111/j.1574-6968.1998.tb12894.x.

Abstract

Glutathione transferase was purified from Ochrobactrum anthropi and its N-terminal sequence was determined to be MKLYYKVGACSLAPHIILSEAGLPY. The apparent molecular mass of the protein (24 kDa) was determined by SDS-polyacrylamide gel electrophoresis analysis. The amino acid sequence obtained showed similarities with known bacterial glutathione transferases in the range of 72-64%. Immunoblotting experiments performed with antisera raised against glutathione transferase from O. anthropi did not show cross-reactivity with two bacterial glutathione transferases belonging to Serratia marcescens and Proteus mirabilis.

MeSH terms

  • Antibody Specificity
  • Bacterial Proteins / genetics
  • Bacterial Proteins / immunology
  • Glutathione Transferase / genetics*
  • Glutathione Transferase / immunology
  • Glutathione Transferase / isolation & purification*
  • Gram-Negative Aerobic Bacteria / enzymology*
  • Gram-Negative Aerobic Bacteria / genetics*
  • Molecular Sequence Data
  • Sequence Homology, Amino Acid

Substances

  • Bacterial Proteins
  • Glutathione Transferase

Associated data

  • GENBANK/P81065