Diagnosis and treatment of a case of cutaneous cytomegalovirus infection with a dramatic clinical presentation

J Am Acad Dermatol. 1998 Feb;38(2 Pt 2):349-51. doi: 10.1016/s0190-9622(98)70581-x.

Abstract

A patient receiving long-term immunosuppressive treatment of systemic lupus erythematosus developed multiple large painful ulcers on her upper body. Histologic analysis showed cytopathic changes typical of cytomegalovirus infection that was confirmed by immunoperoxidase staining and polymerase chain reaction analyses. Treatment with ganciclovir and foscarnet resulted in clinical resolution. No recurrence was evident 6 months later.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Arm
  • Back
  • Biopsy
  • Chronic Disease
  • Combined Modality Therapy
  • Cytomegalovirus Infections / complications
  • Cytomegalovirus Infections / diagnosis*
  • Cytomegalovirus Infections / therapy
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Lupus Erythematosus, Systemic / complications
  • Lupus Erythematosus, Systemic / drug therapy
  • Skin / pathology
  • Skin Diseases, Viral / complications
  • Skin Diseases, Viral / diagnosis*
  • Skin Diseases, Viral / therapy
  • Skin Ulcer / diagnosis
  • Skin Ulcer / etiology
  • Skin Ulcer / therapy

Substances

  • Immunosuppressive Agents